Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Oceanside Pharmaceuticals, priced at $17.8414 per ML under NDC 68682029915. Its NADAC has been published 134 times since Jan 18, 2023.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Oceanside PharmaceuticalsNDC
68682029915
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/17/2025
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
7/1/2019
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 134 times since Jan 18, 2023, and over the history we have for it it has declined 14.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $17.8414 per ML |
|---|---|
| All-time high | $25.7699 (Feb 14, 2024) |
| All-time low | $17.8414 (Sep 17, 2025) |
| Median price | $25.3038 |
| Average price | $23.8681 |
| Largest weekly change | -23.8% (Aug 20, 2025) |
| Weeks tracked | 134 |
| Tracking since | Jan 18, 2023 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
-30.8%
5Y
N/A
All
-14.5%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 41% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Oceanside Pharmaceuticals manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
loteprednol etabonate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Oceanside Pharmaceuticals, is $17.8414 per ML (NDC 68682029915), effective Oct 1, 2025.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has declined 14.5%. It has been tracked across 134 weekly CMS publications since Jan 18, 2023.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Jan 18, 2023, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $17.8414 (Sep 17, 2025) to a high of $25.7699 (Feb 14, 2024), with a median of $25.3038 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOTEPREDNOL ETABONATE 0.5% DRP, is $10.4737 per ML — about 41% below LOTEPREDNOL ETABONATE 0.5% DRP.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 68682029915) is labeled by Oceanside Pharmaceuticals, and CMS classifies it as a generic product.