Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Oceanside Pharmaceuticals, priced at $17.8414 per ML under NDC 68682029915. Its NADAC has been published 134 times since Jan 18, 2023.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Oceanside PharmaceuticalsNDC
68682029915
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/17/2025
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
7/1/2019
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 134 times since Jan 18, 2023, and over the history we have for it it has declined 14.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $17.8414 per ML |
|---|---|
| All-time high | $25.7699 (Feb 14, 2024) |
| All-time low | $17.8414 (Sep 17, 2025) |
| 52-week high | $19.2908 |
| 52-week low | $17.8414 |
| Median price | $25.3038 |
| Average price | $23.8681 |
| Largest weekly change | -23.8% (Aug 20, 2025) |
| Weeks tracked | 134 |
| Tracking since | Jan 18, 2023 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-7.5%
3Y
-30.8%
5Y
N/A
All
-14.5%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 41% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Oceanside Pharmaceuticals, is $17.8414 per ML (NDC 68682029915), effective Oct 1, 2025.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has declined 14.5%. It has been tracked across 134 weekly CMS publications since Jan 18, 2023.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Jan 18, 2023, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $17.8414 (Sep 17, 2025) to a high of $25.7699 (Feb 14, 2024), with a median of $25.3038 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOTEPREDNOL ETABONATE 0.5% DRP, is $10.5316 per ML — about 41% below LOTEPREDNOL ETABONATE 0.5% DRP.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 68682029915) is labeled by Oceanside Pharmaceuticals, and CMS classifies it as a generic product.