Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Bausch & Lomb Americas Inc., priced at $10.4737 per ML under NDC 82260029905. Its NADAC has been published 96 times since Dec 4, 2024.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Bausch & Lomb Americas Inc.NDC
82260029905
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
4/7/2023
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 96 times since Dec 4, 2024, and over the history we have for it it has risen 20.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.4737 per ML |
|---|---|
| All-time high | $20.4008 (Sep 10, 2025) |
| All-time low | $8.7269 (Dec 4, 2024) |
| 52-week high | $20.1780 |
| 52-week low | $10.1799 |
| Median price | $16.3005 |
| Average price | $15.7122 |
| Largest weekly change | +58.5% (Dec 18, 2024) |
| Weeks tracked | 96 |
| Tracking since | Dec 4, 2024 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Bausch & Lomb Americas Inc. manufacturer profile
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Drug market
loteprednol etabonate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Bausch & Lomb Americas Inc., is $10.4737 per ML (NDC 82260029905), effective Sep 30, 2026.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has risen 20.0%. It has been tracked across 96 weekly CMS publications since Dec 4, 2024.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Dec 4, 2024, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $8.7269 (Dec 4, 2024) to a high of $20.4008 (Sep 10, 2025), with a median of $16.3005 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LOTEPREDNOL ETABONATE 0.5% DRP in a comparable dosage form, but none are currently priced below it.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 82260029905) is labeled by Bausch & Lomb Americas Inc., and CMS classifies it as a generic product.