Product Information
ESTRADIOL 0.05 MG PATCH (2/WK) is a generic product labeled by Noven Therapeutics, LLC, priced at $8.5036 per EA under NDC 68968345008. Its NADAC has been published 407 times since Dec 19, 2018.
FDA first approved this application on Oct 29, 2012. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 mg/d
Manufacturer
Noven Therapeutics, LLCNDC
68968345008
Classification
Generic
Dosage Form
FILM, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
Authorized Generic (NDA)
FDA Application
NDA203752FDA Approved
10/29/2012
TE Code
AB3
On Market Since
1/1/2018
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has been published 407 times since Dec 19, 2018, and over the history we have for it it has risen 7.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.5036 per EA |
|---|---|
| All-time high | $9.2907 (Feb 16, 2022) |
| All-time low | $4.9914 (Nov 20, 2024) |
| 52-week high | $8.5036 |
| 52-week low | $7.1482 |
| Median price | $7.2882 |
| Average price | $7.3049 |
| Largest weekly change | +28.3% (Aug 21, 2024) |
| Weeks tracked | 407 |
| Tracking since | Dec 19, 2018 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Noven Therapeutics, LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
estradiol market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.05 MG PATCH (2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.05 MG PATCH (2/WK), manufactured by Noven Therapeutics, LLC, is $8.5036 per EA (NDC 68968345008), effective Sep 30, 2026.
How has the price of ESTRADIOL 0.05 MG PATCH (2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has risen 7.9%. It has been tracked across 407 weekly CMS publications since Dec 19, 2018.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.05 MG PATCH (2/WK)?
Since Dec 19, 2018, the NADAC for ESTRADIOL 0.05 MG PATCH (2/WK) has ranged from a low of $4.9914 (Nov 20, 2024) to a high of $9.2907 (Feb 16, 2022), with a median of $7.2882 per EA.
Are there cheaper alternatives to ESTRADIOL 0.05 MG PATCH (2/WK)?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.05 MG PATCH (2/WK) in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.05 MG PATCH (2/WK)?
ESTRADIOL 0.05 MG PATCH (2/WK) (NDC 68968345008) is labeled by Noven Therapeutics, LLC, and CMS classifies it as a generic product.