Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Westminster Pharmaceuticals LLC, priced at $0.1014 per EA under NDC 69367028909. Its NADAC has been published 266 times since Jul 21, 2021.

FDA first approved this application on Jun 30, 2017. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL XL 300 MG TABLET

Bupropion Hydrochloride
$0.1014per EA

Strength

300 mg/1

NDC

69367028909

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA207224

FDA Approved

6/30/2017

TE Code

AB3

On Market Since

10/1/2017

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 266 times since Jul 21, 2021, and over the history we have for it it has declined 51.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1014 per EA
All-time high$0.2067 (Aug 11, 2021)
All-time low$0.1014 (Aug 19, 2026)
52-week high$0.1492
52-week low$0.1014
Median price$0.1561
Average price$0.1571
Largest weekly change-27.4% (Feb 21, 2024)
Weeks tracked266
Tracking sinceJul 21, 2021

Price History

1W

-2.6%

1M

-9.1%

3M

-12.2%

6M

-1.9%

1Y

-31.6%

3Y

-43.1%

5Y

-50.9%

All

-51.0%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Westminster Pharmaceuticals LLC, is $0.1014 per EA (NDC 69367028909), effective Aug 19, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 51.0%. It has been tracked across 266 weekly CMS publications since Jul 21, 2021.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Jul 21, 2021, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1014 (Aug 19, 2026) to a high of $0.2067 (Aug 11, 2021), with a median of $0.1561 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL XL 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 69367028909) is labeled by Westminster Pharmaceuticals LLC, and CMS classifies it as a generic product.