Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Slate Run Pharmaceuticals LLC, priced at $0.1154 per EA under NDC 70436001106. Its NADAC has been published 360 times since Jul 3, 2019.

BUPROPION HCL XL 300 MG TABLET

bupropion hydrochloride
$0.1154per EA

Strength

300 mg/1

NDC

70436001106

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

5/20/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA210015

On Market Since

12/1/2018

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 360 times since Jul 3, 2019, and over the history we have for it it has declined 68.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1154 per EA
All-time high$0.4702 (Sep 11, 2019)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1741
Average price$0.1914
Largest weekly change-33.9% (Sep 18, 2019)
Weeks tracked360
Tracking sinceJul 3, 2019

Price History

1W

0.0%

1M

0.0%

3M

+7.5%

6M

-8.4%

1Y

-23.3%

3Y

-33.2%

5Y

-43.6%

All

-68.0%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Slate Run Pharmaceuticals LLC, is $0.1154 per EA (NDC 70436001106), effective May 20, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 68.0%. It has been tracked across 360 weekly CMS publications since Jul 3, 2019.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Jul 3, 2019, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.4702 (Sep 11, 2019), with a median of $0.1741 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

Yes. 9 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BUPROPION HCL XL 300 MG TABLET, is $0.1115 per EA — about 3% below BUPROPION HCL XL 300 MG TABLET.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 70436001106) is labeled by Slate Run Pharmaceuticals LLC, and CMS classifies it as a generic product.