Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1115 per EA under NDC 16571086309. Its NADAC has been published 195 times since Oct 5, 2022.

BUPROPION HCL XL 300 MG TABLET

bupropion hydrochloride
$0.1115per EA

Strength

300 mg/1

NDC

16571086309

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA211020

On Market Since

8/1/2022

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 195 times since Oct 5, 2022, and over the history we have for it it has declined 33.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.1988 (Feb 14, 2024)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1515
Average price$0.1511
Largest weekly change-27.4% (Feb 21, 2024)
Weeks tracked195
Tracking sinceOct 5, 2022

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

-35.5%

5Y

N/A

All

-33.9%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.1115 per EA (NDC 16571086309), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 33.9%. It has been tracked across 195 weekly CMS publications since Oct 5, 2022.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Oct 5, 2022, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.1988 (Feb 14, 2024), with a median of $0.1515 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 16571086309) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.