Product Information

BUPROPION HCL SR 100 MG TABLET is a generic product labeled by Slate Run Pharmaceuticals LLC, priced at $0.0957 per EA under NDC 70436005802. Its NADAC has been published 230 times since Dec 23, 2020.

FDA first approved this application on Oct 16, 2018. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL SR 100 MG TABLET

bupropion hydrochloride
$0.0957per EA

Strength

100 mg/1

NDC

70436005802

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

4/23/2025

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA211347

FDA Approved

10/16/2018

TE Code

AB1

On Market Since

11/2/2020

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 230 times since Dec 23, 2020, and over the history we have for it it has declined 35.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0957 per EA
All-time high$0.1536 (Mar 10, 2021)
All-time low$0.0718 (Jul 17, 2024)
Median price$0.1053
Average price$0.1084
Largest weekly change+30.2% (Jun 19, 2024)
Weeks tracked230
Tracking sinceDec 23, 2020

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

-4.4%

5Y

-28.6%

All

-35.0%

Last surveyed May 14, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by Slate Run Pharmaceuticals LLC, is $0.0957 per EA (NDC 70436005802), effective May 14, 2025.

How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 35.0%. It has been tracked across 230 weekly CMS publications since Dec 23, 2020.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?

Since Dec 23, 2020, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0718 (Jul 17, 2024) to a high of $0.1536 (Mar 10, 2021), with a median of $0.1053 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL SR 100 MG TABLET, is $0.0687 per EA — about 28% below BUPROPION HCL SR 100 MG TABLET.

Who manufactures BUPROPION HCL SR 100 MG TABLET?

BUPROPION HCL SR 100 MG TABLET (NDC 70436005802) is labeled by Slate Run Pharmaceuticals LLC, and CMS classifies it as a generic product.