Product Information
ESTRADIOL VALERATE 50 MG/5 ML is a generic product labeled by Xiromed LLC, priced at $18.2988 per ML under NDC 70700027322. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on Apr 28, 2023. Its Orange Book therapeutic-equivalence code is AO.
Strength
10 mg/mL
Manufacturer
Xiromed LLCNDC
70700027322
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR
Effective Date
9/23/2026
Active Ingredients
ESTRADIOL VALERATEApproval Type
Generic (ANDA)
FDA Application
ANDA216656FDA Approved
4/28/2023
TE Code
AO
On Market Since
5/1/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL VALERATE 50 MG/5 ML has been published 129 times since Apr 17, 2024, and over the history we have for it it has risen 9.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.2988 per ML |
|---|---|
| All-time high | $19.3574 (Apr 15, 2026) |
| All-time low | $15.7509 (Jul 17, 2024) |
| 52-week high | $19.3574 |
| 52-week low | $17.2246 |
| Median price | $16.8870 |
| Average price | $17.3011 |
| Largest weekly change | +3.4% (Jan 21, 2026) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol valerate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Xiromed LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Estradiol valerate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESTRADIOL VALERATE 50 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL VALERATE 50 MG/5 ML, manufactured by Xiromed LLC, is $18.2988 per ML (NDC 70700027322), effective Sep 30, 2026.
How has the price of ESTRADIOL VALERATE 50 MG/5 ML changed over time?
Over the history we have for it, the NADAC for ESTRADIOL VALERATE 50 MG/5 ML has risen 9.7%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL VALERATE 50 MG/5 ML?
Since Apr 17, 2024, the NADAC for ESTRADIOL VALERATE 50 MG/5 ML has ranged from a low of $15.7509 (Jul 17, 2024) to a high of $19.3574 (Apr 15, 2026), with a median of $16.8870 per ML.
Are there cheaper alternatives to ESTRADIOL VALERATE 50 MG/5 ML?
No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL VALERATE 50 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ESTRADIOL VALERATE 50 MG/5 ML?
ESTRADIOL VALERATE 50 MG/5 ML (NDC 70700027322) is labeled by Xiromed LLC, and CMS classifies it as a generic product.