Product Information

DIPHENHYDRAMINE 50 MG/ML VIAL is a generic product labeled by Armas Pharmaceuticals Inc., priced at $1.0105 per ML under NDC 72485010105. Its NADAC has been published 105 times since Aug 21, 2024.

FDA first approved this application on Aug 22, 2018. Its Orange Book therapeutic-equivalence code is AP.

DIPHENHYDRAMINE 50 MG/ML VIAL

Diphenhydramine Hydrochloride
$1.0105per ML

Strength

50 mg/mL

NDC

72485010105

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA205723

FDA Approved

8/22/2018

TE Code

AP

On Market Since

5/1/2019

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has been published 105 times since Aug 21, 2024, and over the history we have for it it has declined 33.3%. The table below summarizes its recorded NADAC range and movement.

Current price$1.0105 per ML
All-time high$1.5140 (Sep 11, 2024)
All-time low$0.9816 (Jul 22, 2026)
52-week high$1.3083
52-week low$0.9816
Median price$1.2680
Average price$1.2514
Largest weekly change+10.5% (Aug 20, 2025)
Weeks tracked105
Tracking sinceAug 21, 2024

Price History

1W

+2.9%

1M

+2.9%

3M

+0.7%

6M

-10.8%

1Y

-22.8%

3Y

N/A

5Y

N/A

All

-33.3%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 8% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENHYDRAMINE 50 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 50 MG/ML VIAL, manufactured by Armas Pharmaceuticals Inc., is $1.0105 per ML (NDC 72485010105), effective Aug 19, 2026.

How has the price of DIPHENHYDRAMINE 50 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has declined 33.3%. It has been tracked across 105 weekly CMS publications since Aug 21, 2024.

What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 50 MG/ML VIAL?

Since Aug 21, 2024, the NADAC for DIPHENHYDRAMINE 50 MG/ML VIAL has ranged from a low of $0.9816 (Jul 22, 2026) to a high of $1.5140 (Sep 11, 2024), with a median of $1.2680 per ML.

Are there cheaper alternatives to DIPHENHYDRAMINE 50 MG/ML VIAL?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIPHENHYDRAMINE 50 MG/ML VIAL, is $0.9336 per ML — about 8% below DIPHENHYDRAMINE 50 MG/ML VIAL.

Who manufactures DIPHENHYDRAMINE 50 MG/ML VIAL?

DIPHENHYDRAMINE 50 MG/ML VIAL (NDC 72485010105) is labeled by Armas Pharmaceuticals Inc., and CMS classifies it as a generic product.