Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Bausch & Lomb Americas Inc., priced at $21.8186 per ML under NDC 82260029910. Its NADAC has been published 75 times since Mar 19, 2025.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Bausch & Lomb Americas Inc.NDC
82260029910
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
4/7/2023
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 75 times since Mar 19, 2025, and over the history we have for it it has risen 88.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.8186 per ML |
|---|---|
| All-time high | $22.0153 (Aug 12, 2026) |
| All-time low | $8.9795 (Apr 23, 2025) |
| 52-week high | $22.0153 |
| 52-week low | $19.6333 |
| Median price | $19.9205 |
| Average price | $18.3277 |
| Largest weekly change | +32.0% (May 21, 2025) |
| Weeks tracked | 75 |
| Tracking since | Mar 19, 2025 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 52% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Bausch & Lomb Americas Inc., is $21.8186 per ML (NDC 82260029910), effective Aug 19, 2026.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has risen 88.5%. It has been tracked across 75 weekly CMS publications since Mar 19, 2025.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Mar 19, 2025, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $8.9795 (Apr 23, 2025) to a high of $22.0153 (Aug 12, 2026), with a median of $19.9205 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOTEPREDNOL ETABONATE 0.5% DRP, is $10.5316 per ML — about 52% below LOTEPREDNOL ETABONATE 0.5% DRP.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 82260029910) is labeled by Bausch & Lomb Americas Inc., and CMS classifies it as a generic product.