Product Information
LOTEPREDNOL ETABONATE 0.5% DRP is a generic product labeled by Bausch & Lomb Americas Inc., priced at $21.1990 per ML under NDC 82260029910. Its NADAC has been published 81 times since Mar 19, 2025.
FDA first approved this application on Mar 9, 1998. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/mL
Manufacturer
Bausch & Lomb Americas Inc.NDC
82260029910
Classification
Generic
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
LOTEPREDNOL ETABONATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020583FDA Approved
3/9/1998
TE Code
AB
On Market Since
4/7/2023
Pharmacological Classes
Price Statistics
The NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has been published 81 times since Mar 19, 2025, and over the history we have for it it has risen 83.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $21.1990 per ML |
|---|---|
| All-time high | $22.0153 (Aug 12, 2026) |
| All-time low | $8.9795 (Apr 23, 2025) |
| 52-week high | $22.0153 |
| 52-week low | $19.6396 |
| Median price | $20.2219 |
| Average price | $18.5710 |
| Largest weekly change | +32.0% (May 21, 2025) |
| Weeks tracked | 81 |
| Tracking since | Mar 19, 2025 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Bausch & Lomb Americas Inc. manufacturer profile
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Drug market
loteprednol etabonate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOTEPREDNOL ETABONATE 0.5% DRP?
The current National Average Drug Acquisition Cost (NADAC) for LOTEPREDNOL ETABONATE 0.5% DRP, manufactured by Bausch & Lomb Americas Inc., is $21.1990 per ML (NDC 82260029910), effective Sep 30, 2026.
How has the price of LOTEPREDNOL ETABONATE 0.5% DRP changed over time?
Over the history we have for it, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has risen 83.1%. It has been tracked across 81 weekly CMS publications since Mar 19, 2025.
What are the highest and lowest recorded NADAC prices for LOTEPREDNOL ETABONATE 0.5% DRP?
Since Mar 19, 2025, the NADAC for LOTEPREDNOL ETABONATE 0.5% DRP has ranged from a low of $8.9795 (Apr 23, 2025) to a high of $22.0153 (Aug 12, 2026), with a median of $20.2219 per ML.
Are there cheaper alternatives to LOTEPREDNOL ETABONATE 0.5% DRP?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOTEPREDNOL ETABONATE 0.5% DRP, is $10.4737 per ML — about 51% below LOTEPREDNOL ETABONATE 0.5% DRP.
Who manufactures LOTEPREDNOL ETABONATE 0.5% DRP?
LOTEPREDNOL ETABONATE 0.5% DRP (NDC 82260029910) is labeled by Bausch & Lomb Americas Inc., and CMS classifies it as a generic product.