Digoxin
42 NDCs across 14 manufacturers|39 Generic,3 Brand
Digoxin is used to treat anxiety disorders, atrial fibrillation, atrial flutter, low cardiac output, heart failure and cardiogenic shock, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. FDA's Orange Book lists 15 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $38 million on Digoxin across 1.6 million claims for 371,000 beneficiaries.
Digoxin is available as 42 NDCs from 14 manufacturers (39 generic, 3 brand), with NADAC prices from $0.11 to $12.16 per EA — the most expensive product costs about 110× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
42
39G / 3B
Manufacturers
14
competing in market
Price Spread
$0.11 – $12.16
per EA, 39 of 42 NDCs
7d Activity
avg +2.9% WoW · of 42 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
14 manufacturers producing DIGOXIN(1 pricing outlier)
Frequently Asked Questions
What is Digoxin used to treat?
Digoxin is used to treat anxiety disorders, atrial fibrillation, atrial flutter, low cardiac output, heart failure and cardiogenic shock, per the National Library of Medicine's MED-RT classification.
When did Digoxin become available as a generic?
FDA approved the first generic Digoxin (ANDA) on Jan 1, 1982. The Orange Book currently lists 15 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Digoxin?
In 2024, Medicare Part D spent $38 million on Digoxin across 1.6 million claims for 371,000 beneficiaries.
How many Digoxin products are on the market?
The Digoxin drug market contains 42 NDCs from 14 manufacturers — 39 generic and 3 brand products.
What is the price range for Digoxin?
NADAC reference prices for Digoxin range from $0.1106 to $12.1565 per EA — the most expensive product costs about 110× the cheapest. 3 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Digoxin cheaper than brand?
The average generic NADAC for Digoxin is $0.6295 per EA, versus $11.6289 for brand-labeled products — brand versions average about 18× the generic price.
Which manufacturers make Digoxin?
14 manufacturers list Digoxin in NADAC. Ranked by number of NDCs, the largest are Aurobindo Pharma Limited (5), ANI Pharmaceuticals, Inc. (5), Hikma Pharmaceuticals USA Inc. (5), Amneal Pharmaceuticals of New York LLC (4), Sun Pharmaceutical Industries Inc. (4).
How has the price of Digoxin changed recently?
Over the past 7 days, 34 Digoxin NDCs rose and 0 fell, with a market-wide average change of +2.9%.