Mirtazapine
73 NDCs across 14 manufacturers|71 Generic,2 Brand
Mirtazapine is used to treat depressive disorder, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Jun 14, 1996, and the first generic was approved Jan 24, 2003. FDA's Orange Book lists 47 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $159 million on Mirtazapine across 8.3 million claims for 1.6 million beneficiaries.
Mirtazapine is available as 73 NDCs from 14 manufacturers (71 generic, 2 brand), with NADAC prices from $0.06 to $6.67 per EA — the most expensive product costs about 106× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
73
71G / 2B
Manufacturers
14
competing in market
Price Spread
$0.06 – $6.67
per EA
7d Activity
avg +0.9% WoW · of 73 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Rising Pharma Holdings Inc. manufacturer profile
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Trend hub
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
14 manufacturers producing MIRTAZAPINE(1 pricing outlier)
Frequently Asked Questions
What is Mirtazapine used to treat?
Mirtazapine is used to treat depressive disorder, per the National Library of Medicine's MED-RT classification.
When did Mirtazapine become available as a generic?
FDA approved the first generic Mirtazapine (ANDA) on Jan 24, 2003. The Orange Book currently lists 47 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Mirtazapine?
In 2024, Medicare Part D spent $159 million on Mirtazapine across 8.3 million claims for 1.6 million beneficiaries.
How many Mirtazapine products are on the market?
The Mirtazapine drug market contains 73 NDCs from 14 manufacturers — 71 generic and 2 brand products.
What is the price range for Mirtazapine?
NADAC reference prices for Mirtazapine range from $0.0630 to $6.6731 per EA — the most expensive product costs about 106× the cheapest.
Is generic Mirtazapine cheaper than brand?
The average generic NADAC for Mirtazapine is $0.1599 per EA, versus $6.5180 for brand-labeled products — brand versions average about 41× the generic price.
Which manufacturers make Mirtazapine?
14 manufacturers list Mirtazapine in NADAC. Ranked by number of NDCs, the largest are Rising Pharma Holdings Inc. (11), Aurolife Pharma LLC (10), Mylan Pharmaceuticals Inc. (9), Prasco Laboratories (8), Aurobindo Pharma Limited (6).
How has the price of Mirtazapine changed recently?
Over the past 7 days, 34 Mirtazapine NDCs rose and 35 fell, with a market-wide average change of +0.9%.