Drug Markets/Tacrolimus

Tacrolimus

73 NDCs across 18 manufacturers|66 Generic,7 Brand

Tacrolimus is used to treat atopic dermatitis and graft vs host disease, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Apr 8, 1994, and the first generic was approved Aug 10, 2009. FDA's Orange Book lists 47 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $107 million on Tacrolimus across 671,000 claims for 267,000 beneficiaries.

Tacrolimus is available as 73 NDCs from 18 manufacturers (66 generic, 7 brand), with NADAC prices from $0.13 to $35.63 per EA — the most expensive product costs about 284× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

73

66G / 7B

Manufacturers

18

competing in market

Price Spread

$0.13 – $35.63

per EA, 49 of 73 NDCs

7d Activity

29↑31↓13 flat

avg +1.5% WoW · of 73 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

18 manufacturers producing TACROLIMUS(2 pricing outliers)

Accord Healthcare Inc.
9 NDCs
$0.6737
avg/unit
Glenmark Pharmaceuticals Inc., USA
9 NDCs
$0.7061
avg/unit
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
6 NDCs
$0.9031
avg/unit
Padagis Israel Pharmaceuticals Ltd
6 NDCs
$0.9031
avg/unit
Astellas Pharma US, Inc.
High Outlier
5 NDCs
$11.8119
avg/unit
Major Pharmaceuticals
3 NDCs
$0.3122
avg/unit
Biocon Pharma Inc.
3 NDCs
$0.3122
avg/unit
Jubilant Cadista Pharmaceuticals Inc.
3 NDCs
$0.3122
avg/unit
Mylan Pharmaceuticals Inc.
3 NDCs
$0.3122
avg/unit
Strides Pharma Inc.
3 NDCs
$0.3122
avg/unit
Ascend Laboratories, LLC
3 NDCs
$0.3122
avg/unit
NorthStar Rx LLC
3 NDCs
$0.3122
avg/unit
Sandoz Inc.
3 NDCs
$0.3122
avg/unit
Quallent Pharmaceuticals Health LLC
3 NDCs
$0.3122
avg/unit
Mylan Institutional LLC
3 NDCs
$0.3122
avg/unit
Dr. Reddy's Laboratories Inc.
3 NDCs
$0.3122
avg/unit
American Health Packaging
3 NDCs
$0.3122
avg/unit
Veloxis Pharmaceuticals, Inc
High Outlier
2 NDCs
$6.1904
avg/unit

Drug Portfolio

73 NDCs total, 73 shown

Drug ↕Price 7d Change ↕
PROGRAF 5 MG CAPSULE
$35.6341
per EA
—
PROGRAF 1 MG GRANULE PACKET
$7.4446
per EA
—
PROGRAF 1 MG CAPSULE
$7.3151
per EA
-0.15%
ENVARSUS XR 1 MG TABLET
$6.1904
per EA
—
ENVARSUS XR 1 MG TABLET
$6.1904
per EA
—
PROGRAF 0.2 MG GRANULE PACKET
$5.0042
per EA
-0.01%
PROGRAF 0.5 MG CAPSULE
$3.6618
per EA
+0.08%
TACROLIMUS 0.1% OINTMENT
$0.9925
per GM
—
TACROLIMUS 0.1% OINTMENT
$0.9615
per GM
+9.27%
TACROLIMUS 0.1% OINTMENT
$0.9615
per GM
+9.27%
TACROLIMUS 0.1% OINTMENT
$0.9615
per GM
+9.27%
TACROLIMUS 0.1% OINTMENT
$0.9560
per GM
-0.79%
TACROLIMUS 0.1% OINTMENT
$0.9560
per GM
-0.79%
TACROLIMUS 0.1% OINTMENT
$0.9560
per GM
-0.79%
TACROLIMUS 0.1% OINTMENT
$0.9192
per GM
+2.27%
TACROLIMUS 0.1% OINTMENT
$0.9192
per GM
+2.27%
TACROLIMUS 0.1% OINTMENT
$0.9192
per GM
+2.27%
TACROLIMUS 0.03% OINTMENT
$0.9074
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.9036
per GM
+12.91%
TACROLIMUS 0.03% OINTMENT
$0.9036
per GM
+12.91%
TACROLIMUS 0.03% OINTMENT
$0.9036
per GM
+12.91%
TACROLIMUS 0.1% OINTMENT
$0.8986
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.8830
per GM
+7.86%
TACROLIMUS 0.03% OINTMENT
$0.8830
per GM
+7.86%
TACROLIMUS 0.03% OINTMENT
$0.8830
per GM
+7.86%
TACROLIMUS 0.1% OINTMENT
$0.8823
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.8073
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.7954
per GM
+13.67%
TACROLIMUS 0.03% OINTMENT
$0.7954
per GM
+13.67%
TACROLIMUS 0.03% OINTMENT
$0.7954
per GM
+13.67%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6746
per EA
—
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6591
per EA
-0.84%
TACROLIMUS 0.03% OINTMENT
$0.5924
per GM
—
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1613
per EA
—
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1518
per EA
+0.36%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1465
per EA
—
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1256
per EA
-3.08%

Frequently Asked Questions

What is Tacrolimus used to treat?

Tacrolimus is used to treat atopic dermatitis and graft vs host disease, per the National Library of Medicine's MED-RT classification.

When did Tacrolimus become available as a generic?

FDA approved the first generic Tacrolimus (ANDA) on Aug 10, 2009. The Orange Book currently lists 47 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Tacrolimus?

In 2024, Medicare Part D spent $107 million on Tacrolimus across 671,000 claims for 267,000 beneficiaries.

How many Tacrolimus products are on the market?

The Tacrolimus drug market contains 73 NDCs from 18 manufacturers — 66 generic and 7 brand products.

What is the price range for Tacrolimus?

NADAC reference prices for Tacrolimus range from $0.1256 to $35.6341 per EA — the most expensive product costs about 284× the cheapest. 24 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Tacrolimus cheaper than brand?

The average generic NADAC for Tacrolimus is $0.3133 per EA, versus $10.2058 for brand-labeled products — brand versions average about 33× the generic price.

Which manufacturers make Tacrolimus?

18 manufacturers list Tacrolimus in NADAC. Ranked by number of NDCs, the largest are Accord Healthcare Inc. (9), Glenmark Pharmaceuticals Inc., USA (9), E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. (6), Padagis Israel Pharmaceuticals Ltd (6), Astellas Pharma US, Inc. (5).

How has the price of Tacrolimus changed recently?

Over the past 7 days, 29 Tacrolimus NDCs rose and 31 fell, with a market-wide average change of +1.5%.