Drug Markets/Tacrolimus

Tacrolimus

73 NDCs across 18 manufacturers|66 Generic,7 Brand

Tacrolimus is used to treat atopic dermatitis and graft vs host disease, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved on Apr 8, 1994, and the first generic was approved Aug 10, 2009. FDA's Orange Book lists 47 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $107 million on Tacrolimus across 671,000 claims for 267,000 beneficiaries.

Tacrolimus is available as 73 NDCs from 18 manufacturers (66 generic, 7 brand), with NADAC prices from $0.12 to $35.63 per EA — the most expensive product costs about 290× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

73

66G / 7B

Manufacturers

18

competing in market

Price Spread

$0.12 – $35.63

per EA, 49 of 73 NDCs

7d Activity

46↑14↓13 flat

avg +2.4% WoW · of 73 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Explore this market from other angles

Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.

Top supplier

Glenmark Pharmaceuticals Inc., USA manufacturer profile

Open the supplier page for the manufacturer with the strongest footprint in this market.

Lead class

Calcineurin Inhibitor Immunosuppressant class view

See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.

Trend hub

Latest market trends

Move from this single molecule into the current cross-market mover and volatility view.

Guide

How to interpret NADAC

Review the benchmark methodology behind the prices and spreads shown on this market page.

Manufacturer Breakdown

18 manufacturers producing TACROLIMUS(2 pricing outliers)

Glenmark Pharmaceuticals Inc., USA
9 NDCs
$0.7413
avg/unit
Accord Healthcare Inc.
9 NDCs
$0.6737
avg/unit
Padagis Israel Pharmaceuticals Ltd
6 NDCs
$0.9512
avg/unit
E. Fougera & Co. a division of Fougera Pharmaceuticals Inc.
6 NDCs
$0.9512
avg/unit
Astellas Pharma US, Inc.
High Outlier
5 NDCs
$11.8161
avg/unit
Mylan Pharmaceuticals Inc.
3 NDCs
$0.3214
avg/unit
Dr. Reddy's Laboratories Inc.
3 NDCs
$0.3214
avg/unit
Mylan Institutional LLC
3 NDCs
$0.3214
avg/unit
American Health Packaging
3 NDCs
$0.3214
avg/unit
Sandoz Inc.
3 NDCs
$0.3214
avg/unit
Jubilant Cadista Pharmaceuticals Inc.
3 NDCs
$0.3214
avg/unit
Major Pharmaceuticals
3 NDCs
$0.3214
avg/unit
Quallent Pharmaceuticals Health LLC
3 NDCs
$0.3214
avg/unit
Strides Pharma Inc.
3 NDCs
$0.3214
avg/unit
Biocon Pharma Inc.
3 NDCs
$0.3214
avg/unit
Ascend Laboratories, LLC
3 NDCs
$0.3214
avg/unit
NorthStar Rx LLC
3 NDCs
$0.3214
avg/unit
Veloxis Pharmaceuticals, Inc
High Outlier
2 NDCs
$6.1904
avg/unit

Drug Portfolio

73 NDCs total, 73 shown

Drug ↕Price 7d Change ↕
PROGRAF 5 MG CAPSULE
$35.6341
per EA
—
PROGRAF 1 MG GRANULE PACKET
$7.4446
per EA
—
PROGRAF 1 MG CAPSULE
$7.3273
per EA
+0.17%
ENVARSUS XR 1 MG TABLET
$6.1904
per EA
—
ENVARSUS XR 1 MG TABLET
$6.1904
per EA
—
PROGRAF 0.2 MG GRANULE PACKET
$5.0151
per EA
+0.22%
PROGRAF 0.5 MG CAPSULE
$3.6591
per EA
-0.07%
TACROLIMUS 0.03% OINTMENT
$0.9983
per GM
+10.48%
TACROLIMUS 0.03% OINTMENT
$0.9983
per GM
+10.48%
TACROLIMUS 0.03% OINTMENT
$0.9983
per GM
+10.48%
TACROLIMUS 0.1% OINTMENT
$0.9925
per GM
—
TACROLIMUS 0.1% OINTMENT
$0.9816
per GM
+2.68%
TACROLIMUS 0.1% OINTMENT
$0.9816
per GM
+2.68%
TACROLIMUS 0.1% OINTMENT
$0.9816
per GM
+2.68%
TACROLIMUS 0.1% OINTMENT
$0.9701
per GM
+0.89%
TACROLIMUS 0.1% OINTMENT
$0.9701
per GM
+0.89%
TACROLIMUS 0.1% OINTMENT
$0.9701
per GM
+0.89%
TACROLIMUS 0.1% OINTMENT
$0.9426
per GM
+2.55%
TACROLIMUS 0.1% OINTMENT
$0.9426
per GM
+2.55%
TACROLIMUS 0.1% OINTMENT
$0.9426
per GM
+2.55%
TACROLIMUS 0.03% OINTMENT
$0.9270
per GM
+4.99%
TACROLIMUS 0.03% OINTMENT
$0.9270
per GM
+4.99%
TACROLIMUS 0.03% OINTMENT
$0.9270
per GM
+4.99%
TACROLIMUS 0.03% OINTMENT
$0.9074
per GM
—
TACROLIMUS 0.1% OINTMENT
$0.8986
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.8878
per GM
+11.61%
TACROLIMUS 0.03% OINTMENT
$0.8878
per GM
+11.61%
TACROLIMUS 0.03% OINTMENT
$0.8878
per GM
+11.61%
TACROLIMUS 0.1% OINTMENT
$0.8823
per GM
—
TACROLIMUS 0.03% OINTMENT
$0.8073
per GM
—
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6881
per EA
+4.39%
TACROLIMUS 5 MG CAPSULE (IMMEDIATE RELEASE)
$0.6746
per EA
—
TACROLIMUS 0.03% OINTMENT
$0.5924
per GM
—
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1613
per EA
—
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 1 MG CAPSULE (IMMEDIATE RELEASE)
$0.1535
per EA
+1.12%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1465
per EA
—
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%
TACROLIMUS 0.5 MG CAPSULE (IMMEDIATE RELEASE)
$0.1227
per EA
-2.25%

Frequently Asked Questions

What is Tacrolimus used to treat?

Tacrolimus is used to treat atopic dermatitis and graft vs host disease, per the National Library of Medicine's MED-RT classification.

When did Tacrolimus become available as a generic?

FDA approved the first generic Tacrolimus (ANDA) on Aug 10, 2009. The Orange Book currently lists 47 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.

How much does Medicare spend on Tacrolimus?

In 2024, Medicare Part D spent $107 million on Tacrolimus across 671,000 claims for 267,000 beneficiaries.

How many Tacrolimus products are on the market?

The Tacrolimus drug market contains 73 NDCs from 18 manufacturers — 66 generic and 7 brand products.

What is the price range for Tacrolimus?

NADAC reference prices for Tacrolimus range from $0.1227 to $35.6341 per EA — the most expensive product costs about 290× the cheapest. 24 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Is generic Tacrolimus cheaper than brand?

The average generic NADAC for Tacrolimus is $0.3219 per EA, versus $10.2087 for brand-labeled products — brand versions average about 32× the generic price.

Which manufacturers make Tacrolimus?

18 manufacturers list Tacrolimus in NADAC. Ranked by number of NDCs, the largest are Glenmark Pharmaceuticals Inc., USA (9), Accord Healthcare Inc. (9), Padagis Israel Pharmaceuticals Ltd (6), E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. (6), Astellas Pharma US, Inc. (5).

How has the price of Tacrolimus changed recently?

Over the past 7 days, 46 Tacrolimus NDCs rose and 14 fell, with a market-wide average change of +2.4%.