Product Information
PREMPRO 0.45-1.5 MG TABLET is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $8.6836 per EA under NDC 00046110611. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Nov 17, 1995.
Strength
.45; 1.5 mg/1; mg/1
NDC
00046110611
Classification
Brand
Dosage Form
TABLET, SUGAR COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ESTROGENS, CONJUGATED; MEDROXYPROGESTERONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA020527FDA Approved
11/17/1995
On Market Since
9/21/2009
Price Statistics
The NADAC for PREMPRO 0.45-1.5 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 153.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.6836 per EA |
|---|---|
| All-time high | $8.7001 (Jun 10, 2026) |
| All-time low | $3.4260 (Nov 28, 2013) |
| 52-week high | $8.7001 |
| 52-week low | $8.4595 |
| Median price | $6.9390 |
| Average price | $6.7150 |
| Largest weekly change | +9.4% (Jun 8, 2016) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the conjugated estrogens and medroxyprogesterone acetate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
conjugated estrogens and medroxyprogesterone acetate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PREMPRO 0.45-1.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PREMPRO 0.45-1.5 MG TABLET, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $8.6836 per EA (NDC 00046110611), effective Sep 30, 2026.
How has the price of PREMPRO 0.45-1.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for PREMPRO 0.45-1.5 MG TABLET has risen 153.5%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PREMPRO 0.45-1.5 MG TABLET?
Since Nov 28, 2013, the NADAC for PREMPRO 0.45-1.5 MG TABLET has ranged from a low of $3.4260 (Nov 28, 2013) to a high of $8.7001 (Jun 10, 2026), with a median of $6.9390 per EA.
Are there cheaper alternatives to PREMPRO 0.45-1.5 MG TABLET?
No other NADAC-published product currently shares the active ingredient and strength of PREMPRO 0.45-1.5 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures PREMPRO 0.45-1.5 MG TABLET?
PREMPRO 0.45-1.5 MG TABLET (NDC 00046110611) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.