Product Information
PREMPRO 0.625-2.5 MG TABLET is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $8.6774 per EA under NDC 00046110711. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Nov 17, 1995.
Strength
.625; 2.5 mg/1; mg/1
NDC
00046110711
Classification
Brand
Dosage Form
TABLET, SUGAR COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ESTROGENS, CONJUGATED; MEDROXYPROGESTERONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA020527FDA Approved
11/17/1995
On Market Since
9/21/2009
Price Statistics
The NADAC for PREMPRO 0.625-2.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 153.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.6774 per EA |
|---|---|
| All-time high | $8.6844 (May 13, 2026) |
| All-time low | $3.4189 (Nov 28, 2013) |
| 52-week high | $8.6844 |
| 52-week low | $8.4559 |
| Median price | $6.9579 |
| Average price | $6.7193 |
| Largest weekly change | +9.4% (Jun 8, 2016) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the conjugated estrogens and medroxyprogesterone acetate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of PREMPRO 0.625-2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for PREMPRO 0.625-2.5 MG TABLET, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $8.6774 per EA (NDC 00046110711), effective Aug 19, 2026.
How has the price of PREMPRO 0.625-2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for PREMPRO 0.625-2.5 MG TABLET has risen 153.8%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for PREMPRO 0.625-2.5 MG TABLET?
Since Nov 28, 2013, the NADAC for PREMPRO 0.625-2.5 MG TABLET has ranged from a low of $3.4189 (Nov 28, 2013) to a high of $8.6844 (May 13, 2026), with a median of $6.9579 per EA.
Are there cheaper alternatives to PREMPRO 0.625-2.5 MG TABLET?
No other NADAC-published product currently shares the active ingredient and strength of PREMPRO 0.625-2.5 MG TABLET in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures PREMPRO 0.625-2.5 MG TABLET?
PREMPRO 0.625-2.5 MG TABLET (NDC 00046110711) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.