Product Information

PREMPRO 0.625-2.5 MG TABLET is a brand product labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., priced at $8.6706 per EA under NDC 00046110711. Its NADAC has been published 657 times since Nov 28, 2013.

PREMPRO 0.625-2.5 MG TABLET

conjugated estrogens and medroxyprogesterone acetate
$8.6706per EA

Strength

.625; 2.5 mg/1; mg/1

NDC

00046110711

Classification

Brand

Dosage Form

TABLET, SUGAR COATED

Route

ORAL

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA020527

On Market Since

9/21/2009

Pharmacological Classes

Estrogen Receptor Agonists
Estrogen
Estrogens
Conjugated (USP)
Progesterone Congeners
Progestin

Price Statistics

The NADAC for PREMPRO 0.625-2.5 MG TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 153.6%. The table below summarizes its recorded NADAC range and movement.

Current price$8.6706 per EA
All-time high$8.6844 (May 13, 2026)
All-time low$3.4189 (Nov 28, 2013)
52-week high$8.6844
52-week low$8.4559
Median price$6.9528
Average price$6.6955
Largest weekly change+9.4% (Jun 8, 2016)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-0.1%

3M

-0.2%

6M

+2.5%

1Y

+2.4%

3Y

+7.7%

5Y

+18.8%

All

+153.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the conjugated estrogens and medroxyprogesterone acetate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of PREMPRO 0.625-2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for PREMPRO 0.625-2.5 MG TABLET, manufactured by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., is $8.6706 per EA (NDC 00046110711), effective Jun 24, 2026.

How has the price of PREMPRO 0.625-2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for PREMPRO 0.625-2.5 MG TABLET has risen 153.6%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for PREMPRO 0.625-2.5 MG TABLET?

Since Nov 28, 2013, the NADAC for PREMPRO 0.625-2.5 MG TABLET has ranged from a low of $3.4189 (Nov 28, 2013) to a high of $8.6844 (May 13, 2026), with a median of $6.9528 per EA.

Are there cheaper alternatives to PREMPRO 0.625-2.5 MG TABLET?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of PREMPRO 0.625-2.5 MG TABLET, so no direct lower-cost alternative is listed.

Who manufactures PREMPRO 0.625-2.5 MG TABLET?

PREMPRO 0.625-2.5 MG TABLET (NDC 00046110711) is labeled by Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc., and CMS classifies it as a brand product.