Historical record - last NADAC effective date: 2/23/2022
Product Information
DIFFERIN 0.3% GEL PUMP is a brand product labeled by Galderma Laboratories, L.P., priced at $11.6331 per GM under NDC 00299591825. Its NADAC has been published 372 times since Nov 28, 2013.
FDA first approved this application on Jun 19, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
3 mg/g
Manufacturer
Galderma Laboratories, L.P.NDC
00299591825
Classification
Brand
Dosage Form
GEL
Route
TOPICAL
Effective Date
2/23/2022
Active Ingredients
ADAPALENEApproval Type
New Drug (NDA)
FDA Application
NDA021753FDA Approved
6/19/2007
TE Code
AB
On Market Since
9/15/2009
Pharmacological Classes
Price Statistics
The NADAC for DIFFERIN 0.3% GEL PUMP has been published 372 times since Nov 28, 2013, and over the history we have for it it has risen 113.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.6331 per GM |
|---|---|
| All-time high | $11.9840 (May 11, 2016) |
| All-time low | $5.4610 (Nov 28, 2013) |
| Median price | $11.6594 |
| Average price | $10.7734 |
| Largest weekly change | +50.0% (Jul 9, 2014) |
| Weeks tracked | 372 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
-0.5%
All
+113.0%
Last surveyed Dec 28, 2022 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 96% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Galderma Laboratories, L.P. manufacturer profile
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Drug market
adapalene market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DIFFERIN 0.3% GEL PUMP?
The current National Average Drug Acquisition Cost (NADAC) for DIFFERIN 0.3% GEL PUMP, manufactured by Galderma Laboratories, L.P., is $11.6331 per GM (NDC 00299591825), effective Dec 28, 2022.
How has the price of DIFFERIN 0.3% GEL PUMP changed over time?
Over the history we have for it, the NADAC for DIFFERIN 0.3% GEL PUMP has risen 113.0%. It has been tracked across 372 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DIFFERIN 0.3% GEL PUMP?
Since Nov 28, 2013, the NADAC for DIFFERIN 0.3% GEL PUMP has ranged from a low of $5.4610 (Nov 28, 2013) to a high of $11.9840 (May 11, 2016), with a median of $11.6594 per GM.
Are there cheaper alternatives to DIFFERIN 0.3% GEL PUMP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ADAPALENE 0.3% GEL, is $0.5038 per GM — about 96% below DIFFERIN 0.3% GEL PUMP.
Who manufactures DIFFERIN 0.3% GEL PUMP?
DIFFERIN 0.3% GEL PUMP (NDC 00299591825) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.