Historical record - last NADAC effective date: 2/23/2022
Product Information
DIFFERIN 0.3% GEL PUMP is a brand product labeled by Galderma Laboratories, L.P., priced at $11.6331 per GM under NDC 00299591825. Its NADAC has been published 372 times since Nov 28, 2013.
FDA first approved this application on Jun 19, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the adapalene market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
3 mg/g
Manufacturer
Galderma Laboratories, L.P.NDC
00299591825
Classification
Brand
Dosage Form
GEL
Route
TOPICAL
Effective Date
2/23/2022
Active Ingredients
ADAPALENEApproval Type
New Drug (NDA)
FDA Application
NDA021753FDA Approved
6/19/2007
TE Code
AB
On Market Since
9/15/2009
Pharmacological Classes
Price Statistics
The NADAC for DIFFERIN 0.3% GEL PUMP has been published 372 times since Nov 28, 2013, and over the history we have for it it has risen 113.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.6331 per GM |
|---|---|
| All-time high | $11.9840 (May 11, 2016) |
| All-time low | $5.4610 (Nov 28, 2013) |
| Median price | $11.6594 |
| Average price | $10.7734 |
| Largest weekly change | +50.0% (Jul 9, 2014) |
| Weeks tracked | 372 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
-0.5%
All
+113.0%
Last surveyed Dec 28, 2022 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 96% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIFFERIN 0.3% GEL PUMP?
The current National Average Drug Acquisition Cost (NADAC) for DIFFERIN 0.3% GEL PUMP, manufactured by Galderma Laboratories, L.P., is $11.6331 per GM (NDC 00299591825), effective Dec 28, 2022.
How has the price of DIFFERIN 0.3% GEL PUMP changed over time?
Over the history we have for it, the NADAC for DIFFERIN 0.3% GEL PUMP has risen 113.0%. It has been tracked across 372 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DIFFERIN 0.3% GEL PUMP?
Since Nov 28, 2013, the NADAC for DIFFERIN 0.3% GEL PUMP has ranged from a low of $5.4610 (Nov 28, 2013) to a high of $11.9840 (May 11, 2016), with a median of $11.6594 per GM.
Are there cheaper alternatives to DIFFERIN 0.3% GEL PUMP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ADAPALENE 0.3% GEL, is $0.5094 per GM — about 96% below DIFFERIN 0.3% GEL PUMP.
Who manufactures DIFFERIN 0.3% GEL PUMP?
DIFFERIN 0.3% GEL PUMP (NDC 00299591825) is labeled by Galderma Laboratories, L.P., and CMS classifies it as a brand product.