Product Information
ESTRADIOL 0.0375 MG PATCH(2/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $7.8091 per EA under NDC 00378462026. Its NADAC has been published 391 times since Jan 2, 2019.
Strength
.0375 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378462026
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA206685On Market Since
11/1/2018
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.0375 MG PATCH(2/WK) has been published 391 times since Jan 2, 2019, and over the history we have for it it has declined 2.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.8091 per EA |
|---|---|
| All-time high | $10.3341 (Apr 13, 2022) |
| All-time low | $5.3236 (Nov 20, 2024) |
| 52-week high | $7.8091 |
| 52-week low | $6.6398 |
| Median price | $7.1291 |
| Average price | $7.3481 |
| Largest weekly change | +29.5% (Mar 23, 2022) |
| Weeks tracked | 391 |
| Tracking since | Jan 2, 2019 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.0375 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.0375 MG PATCH(2/WK), manufactured by Mylan Pharmaceuticals Inc., is $7.8091 per EA (NDC 00378462026), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.0375 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.0375 MG PATCH(2/WK) has declined 2.8%. It has been tracked across 391 weekly CMS publications since Jan 2, 2019.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.0375 MG PATCH(2/WK)?
Since Jan 2, 2019, the NADAC for ESTRADIOL 0.0375 MG PATCH(2/WK) has ranged from a low of $5.3236 (Nov 20, 2024) to a high of $10.3341 (Apr 13, 2022), with a median of $7.1291 per EA.
Are there cheaper alternatives to ESTRADIOL 0.0375 MG PATCH(2/WK)?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.0375 MG PATCH(2/WK), but none are currently priced below it.
Who manufactures ESTRADIOL 0.0375 MG PATCH(2/WK)?
ESTRADIOL 0.0375 MG PATCH(2/WK) (NDC 00378462026) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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