Product Information
ESTRADIOL 0.025 MG PATCH(2/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $7.7586 per EA under NDC 00378464426. Its NADAC has been published 589 times since Mar 18, 2015.
Strength
.025 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378464426
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA201675On Market Since
12/19/2014
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has been published 589 times since Mar 18, 2015, and over the history we have for it it has declined 10.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.7586 per EA |
|---|---|
| All-time high | $10.9520 (Jan 12, 2022) |
| All-time low | $4.9692 (Nov 20, 2024) |
| 52-week high | $7.7586 |
| 52-week low | $6.2985 |
| Median price | $7.7586 |
| Average price | $7.7236 |
| Largest weekly change | +47.0% (Dec 22, 2021) |
| Weeks tracked | 589 |
| Tracking since | Mar 18, 2015 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.025 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.025 MG PATCH(2/WK), manufactured by Mylan Pharmaceuticals Inc., is $7.7586 per EA (NDC 00378464426), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.025 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has declined 10.4%. It has been tracked across 589 weekly CMS publications since Mar 18, 2015.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.025 MG PATCH(2/WK)?
Since Mar 18, 2015, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has ranged from a low of $4.9692 (Nov 20, 2024) to a high of $10.9520 (Jan 12, 2022), with a median of $7.7586 per EA.
Are there cheaper alternatives to ESTRADIOL 0.025 MG PATCH(2/WK)?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.025 MG PATCH(2/WK), but none are currently priced below it.
Who manufactures ESTRADIOL 0.025 MG PATCH(2/WK)?
ESTRADIOL 0.025 MG PATCH(2/WK) (NDC 00378464426) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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