Product Information
ESTRADIOL 0.025 MG PATCH(2/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $7.6199 per EA under NDC 00378464426. Its NADAC has been published 597 times since Mar 18, 2015.
FDA first approved this application on Dec 19, 2014. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.025 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378464426
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA201675FDA Approved
12/19/2014
TE Code
AB1
On Market Since
12/19/2014
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has been published 597 times since Mar 18, 2015, and over the history we have for it it has declined 12.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.6199 per EA |
|---|---|
| All-time high | $10.9520 (Jan 12, 2022) |
| All-time low | $4.9692 (Nov 20, 2024) |
| 52-week high | $7.8302 |
| 52-week low | $6.2985 |
| Median price | $7.7586 |
| Average price | $7.7244 |
| Largest weekly change | +47.0% (Dec 22, 2021) |
| Weeks tracked | 597 |
| Tracking since | Mar 18, 2015 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.025 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.025 MG PATCH(2/WK), manufactured by Mylan Pharmaceuticals Inc., is $7.6199 per EA (NDC 00378464426), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.025 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has declined 12.0%. It has been tracked across 597 weekly CMS publications since Mar 18, 2015.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.025 MG PATCH(2/WK)?
Since Mar 18, 2015, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has ranged from a low of $4.9692 (Nov 20, 2024) to a high of $10.9520 (Jan 12, 2022), with a median of $7.7586 per EA.
Are there cheaper alternatives to ESTRADIOL 0.025 MG PATCH(2/WK)?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.025 MG PATCH(2/WK) in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.025 MG PATCH(2/WK)?
ESTRADIOL 0.025 MG PATCH(2/WK) (NDC 00378464426) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.