Product Information
ESTRADIOL 0.025 MG PATCH(2/WK) is a generic product labeled by Sandoz Inc., priced at $7.6199 per EA under NDC 00781712983. Its NADAC has been published 585 times since Jun 10, 2015.
FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.025 mg/d
Manufacturer
Sandoz Inc.NDC
00781712983
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Authorized Generic (NDA)
FDA Application
NDA020538FDA Approved
1/8/1999
TE Code
AB1
On Market Since
12/22/2014
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has been published 585 times since Jun 10, 2015, and over the history we have for it it has declined 15.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.6199 per EA |
|---|---|
| All-time high | $10.9520 (Jan 12, 2022) |
| All-time low | $4.9692 (Nov 20, 2024) |
| 52-week high | $7.8302 |
| 52-week low | $6.2985 |
| Median price | $7.7344 |
| Average price | $7.7013 |
| Largest weekly change | +47.0% (Dec 22, 2021) |
| Weeks tracked | 585 |
| Tracking since | Jun 10, 2015 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.025 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.025 MG PATCH(2/WK), manufactured by Sandoz Inc., is $7.6199 per EA (NDC 00781712983), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.025 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has declined 15.4%. It has been tracked across 585 weekly CMS publications since Jun 10, 2015.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.025 MG PATCH(2/WK)?
Since Jun 10, 2015, the NADAC for ESTRADIOL 0.025 MG PATCH(2/WK) has ranged from a low of $4.9692 (Nov 20, 2024) to a high of $10.9520 (Jan 12, 2022), with a median of $7.7344 per EA.
Are there cheaper alternatives to ESTRADIOL 0.025 MG PATCH(2/WK)?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.025 MG PATCH(2/WK) in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.025 MG PATCH(2/WK)?
ESTRADIOL 0.025 MG PATCH(2/WK) (NDC 00781712983) is labeled by Sandoz Inc., and CMS classifies it as a generic product.