Product Information
TRETINOIN 0.05% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $4.2434 per GM under NDC 00378809045. Its NADAC has been published 391 times since Jan 2, 2019.
Strength
.5 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378809045
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA207955On Market Since
11/14/2018
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% GEL has been published 391 times since Jan 2, 2019, and over the history we have for it it has declined 17.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.2434 per GM |
|---|---|
| All-time high | $5.8382 (Apr 15, 2020) |
| All-time low | $3.2879 (Nov 20, 2024) |
| 52-week high | $4.3027 |
| 52-week low | $3.4103 |
| Median price | $4.2565 |
| Average price | $4.3974 |
| Largest weekly change | +27.5% (Jun 19, 2024) |
| Weeks tracked | 391 |
| Tracking since | Jan 2, 2019 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 81% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% GEL, manufactured by Mylan Pharmaceuticals Inc., is $4.2434 per GM (NDC 00378809045), effective Jun 24, 2026.
How has the price of TRETINOIN 0.05% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% GEL has declined 17.9%. It has been tracked across 391 weekly CMS publications since Jan 2, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% GEL?
Since Jan 2, 2019, the NADAC for TRETINOIN 0.05% GEL has ranged from a low of $3.2879 (Nov 20, 2024) to a high of $5.8382 (Apr 15, 2020), with a median of $4.2565 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% GEL?
Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, RETIN-A 0.05% CREAM, is $0.7904 per GM — about 81% below TRETINOIN 0.05% GEL.
Who manufactures TRETINOIN 0.05% GEL?
TRETINOIN 0.05% GEL (NDC 00378809045) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification