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Product Information

TRETINOIN 0.05% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $4.0004 per GM under NDC 00378809045. Its NADAC has been published 399 times since Jan 2, 2019.

FDA first approved this application on Aug 13, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TRETINOIN 0.05% GEL

Tretinoin
$4.0004per GM

Strength

.5 mg/g

NDC

00378809045

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

TRETINOIN

Approval Type

Generic (ANDA)

FDA Application

ANDA207955

FDA Approved

8/13/2015

TE Code

AB

On Market Since

11/14/2018

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for TRETINOIN 0.05% GEL has been published 399 times since Jan 2, 2019, and over the history we have for it it has declined 22.6%. The table below summarizes its recorded NADAC range and movement.

Current price$4.0004 per GM
All-time high$5.8382 (Apr 15, 2020)
All-time low$3.2879 (Nov 20, 2024)
52-week high$4.3027
52-week low$3.4103
Median price$4.2497
Average price$4.3926
Largest weekly change+27.5% (Jun 19, 2024)
Weeks tracked399
Tracking sinceJan 2, 2019

Price History

1W

-3.3%

1M

-3.3%

3M

-5.3%

6M

+4.2%

1Y

-1.7%

3Y

-4.6%

5Y

-28.2%

All

-22.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Tretinoin market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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00536141226•Rugby Laboratories
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Frequently asked questions

What is the NADAC price of TRETINOIN 0.05% GEL?

The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% GEL, manufactured by Mylan Pharmaceuticals Inc., is $4.0004 per GM (NDC 00378809045), effective Aug 19, 2026.

How has the price of TRETINOIN 0.05% GEL changed over time?

Over the history we have for it, the NADAC for TRETINOIN 0.05% GEL has declined 22.6%. It has been tracked across 399 weekly CMS publications since Jan 2, 2019.

What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% GEL?

Since Jan 2, 2019, the NADAC for TRETINOIN 0.05% GEL has ranged from a low of $3.2879 (Nov 20, 2024) to a high of $5.8382 (Apr 15, 2020), with a median of $4.2497 per GM.

Are there cheaper alternatives to TRETINOIN 0.05% GEL?

No other NADAC-published product currently shares the active ingredient and strength of TRETINOIN 0.05% GEL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures TRETINOIN 0.05% GEL?

TRETINOIN 0.05% GEL (NDC 00378809045) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.