Product Information
TRETINOIN 0.05% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $3.9328 per GM under NDC 00378809045. Its NADAC has been published 405 times since Jan 2, 2019.
FDA first approved this application on Aug 13, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378809045
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA207955FDA Approved
8/13/2015
TE Code
AB
On Market Since
11/14/2018
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% GEL has been published 405 times since Jan 2, 2019, and over the history we have for it it has declined 23.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.9328 per GM |
|---|---|
| All-time high | $5.8382 (Apr 15, 2020) |
| All-time low | $3.2879 (Nov 20, 2024) |
| 52-week high | $4.3027 |
| 52-week low | $3.4103 |
| Median price | $4.2497 |
| Average price | $4.3865 |
| Largest weekly change | +27.5% (Jun 19, 2024) |
| Weeks tracked | 405 |
| Tracking since | Jan 2, 2019 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Tretinoin market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
Tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% GEL, manufactured by Mylan Pharmaceuticals Inc., is $3.9328 per GM (NDC 00378809045), effective Sep 30, 2026.
How has the price of TRETINOIN 0.05% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% GEL has declined 23.9%. It has been tracked across 405 weekly CMS publications since Jan 2, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% GEL?
Since Jan 2, 2019, the NADAC for TRETINOIN 0.05% GEL has ranged from a low of $3.2879 (Nov 20, 2024) to a high of $5.8382 (Apr 15, 2020), with a median of $4.2497 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% GEL?
No other NADAC-published product currently shares the active ingredient and strength of TRETINOIN 0.05% GEL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TRETINOIN 0.05% GEL?
TRETINOIN 0.05% GEL (NDC 00378809045) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.