Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Padagis US LLC, priced at $0.4851 per GM under NDC 00574222545. Its NADAC has been published 465 times since Aug 2, 2017.
Strength
.25 mg/g
Manufacturer
Padagis US LLCNDC
00574222545
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA075264On Market Since
6/15/2017
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 465 times since Aug 2, 2017, and over the history we have for it it has declined 82.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4851 per GM |
|---|---|
| All-time high | $2.7125 (Aug 16, 2017) |
| All-time low | $0.4851 (Jun 17, 2026) |
| 52-week high | $0.9756 |
| 52-week low | $0.4851 |
| Median price | $1.7181 |
| Average price | $1.5414 |
| Largest weekly change | +44.4% (Jun 19, 2024) |
| Weeks tracked | 465 |
| Tracking since | Aug 2, 2017 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Padagis US LLC, is $0.4851 per GM (NDC 00574222545), effective Jun 24, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 82.1%. It has been tracked across 465 weekly CMS publications since Aug 2, 2017.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Aug 2, 2017, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.4851 (Jun 17, 2026) to a high of $2.7125 (Aug 16, 2017), with a median of $1.7181 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
3 NADAC-published products share the same active ingredient, strength, and dosage form as TRETINOIN 0.025% CREAM, but none are currently priced below it.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 00574222545) is labeled by Padagis US LLC, and CMS classifies it as a generic product.
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Same classification