Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.4684 per GM under NDC 16714027002. Its NADAC has been published 94 times since Nov 6, 2024.
FDA first approved this application on Jan 5, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
NorthStar Rx LLCNDC
16714027002
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA215713FDA Approved
1/5/2023
TE Code
AB
On Market Since
1/5/2023
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 94 times since Nov 6, 2024, and over the history we have for it it has declined 37.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4684 per GM |
|---|---|
| All-time high | $0.9756 (Dec 10, 2025) |
| All-time low | $0.4684 (Aug 19, 2026) |
| 52-week high | $0.9756 |
| 52-week low | $0.4684 |
| Median price | $0.7959 |
| Average price | $0.7651 |
| Largest weekly change | -19.3% (May 20, 2026) |
| Weeks tracked | 94 |
| Tracking since | Nov 6, 2024 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by NorthStar Rx LLC, is $0.4684 per GM (NDC 16714027002), effective Aug 19, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 37.3%. It has been tracked across 94 weekly CMS publications since Nov 6, 2024.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Nov 6, 2024, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.4684 (Aug 19, 2026) to a high of $0.9756 (Dec 10, 2025), with a median of $0.7959 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.025% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 16714027002) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.