Product Information

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $2.2666 per EA under NDC 00378876693. Its NADAC has been published 316 times since Jun 10, 2020.

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM

Buprenorphine and Naloxone
$2.2666per EA
DEA Schedule CIII

Strength

4; 1 mg/1; mg/1

NDC

00378876693

Classification

Generic

Dosage Form

FILM

Route

BUCCAL; SUBLINGUAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA211785

On Market Since

4/17/2020

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has been published 316 times since Jun 10, 2020, and over the history we have for it it has declined 53.4%. The table below summarizes its recorded NADAC range and movement.

Current price$2.2666 per EA
All-time high$5.1890 (Dec 16, 2020)
All-time low$2.2093 (Nov 20, 2024)
52-week high$3.5744
52-week low$2.2214
Median price$3.8464
Average price$3.9321
Largest weekly change+50.3% (Aug 21, 2024)
Weeks tracked316
Tracking sinceJun 10, 2020

Price History

1W

0.0%

1M

+0.4%

3M

+2.0%

6M

-18.2%

1Y

-34.1%

3Y

-42.6%

5Y

-55.9%

All

-53.4%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM, manufactured by Mylan Pharmaceuticals Inc., is $2.2666 per EA (NDC 00378876693), effective Jun 24, 2026.

How has the price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has declined 53.4%. It has been tracked across 316 weekly CMS publications since Jun 10, 2020.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

Since Jun 10, 2020, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has ranged from a low of $2.2093 (Nov 20, 2024) to a high of $5.1890 (Dec 16, 2020), with a median of $3.8464 per EA.

Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

2 NADAC-published products share the same active ingredient, strength, and dosage form as BUPRENORPHINE-NALOXONE 4-1 MG SL FILM, but none are currently priced below it.

Who manufactures BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM (NDC 00378876693) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.