Product Information

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM is a generic product labeled by Alvogen Inc., priced at $2.5307 per EA under NDC 47781035603. Its NADAC has been published 379 times since May 22, 2019.

FDA first approved this application on Jan 24, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM

Buprenorphine and Naloxone
$2.5307per EA
DEA Schedule CIII

Strength

4; 1 mg/1; mg/1

Manufacturer

Alvogen Inc.

NDC

47781035603

Classification

Generic

Dosage Form

FILM

Route

BUCCAL; SUBLINGUAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA205954

FDA Approved

1/24/2019

TE Code

AB

On Market Since

2/11/2019

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has been published 379 times since May 22, 2019, and over the history we have for it it has declined 54.3%. The table below summarizes its recorded NADAC range and movement.

Current price$2.5307 per EA
All-time high$5.5517 (Jan 15, 2020)
All-time low$2.2093 (Nov 20, 2024)
52-week high$3.5744
52-week low$2.2214
Median price$4.0662
Average price$4.1029
Largest weekly change+50.3% (Aug 21, 2024)
Weeks tracked379
Tracking sinceMay 22, 2019

Price History

1W

+7.7%

1M

+7.7%

3M

+12.1%

6M

+7.9%

1Y

-29.2%

3Y

-31.9%

5Y

-46.7%

All

-54.3%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM, manufactured by Alvogen Inc., is $2.5307 per EA (NDC 47781035603), effective Aug 19, 2026.

How has the price of BUPRENORPHINE-NALOXONE 4-1 MG SL FILM changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has declined 54.3%. It has been tracked across 379 weekly CMS publications since May 22, 2019.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

Since May 22, 2019, the NADAC for BUPRENORPHINE-NALOXONE 4-1 MG SL FILM has ranged from a low of $2.2093 (Nov 20, 2024) to a high of $5.5517 (Jan 15, 2020), with a median of $4.0662 per EA.

Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE-NALOXONE 4-1 MG SL FILM in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPRENORPHINE-NALOXONE 4-1 MG SL FILM?

BUPRENORPHINE-NALOXONE 4-1 MG SL FILM (NDC 47781035603) is labeled by Alvogen Inc., and CMS classifies it as a generic product.