Product Information
TRETINOIN 0.025% GEL is a generic product labeled by Padagis US LLC, priced at $3.7790 per GM under NDC 00574232515. Its NADAC has been published 487 times since Apr 26, 2017.
FDA first approved this application on Feb 22, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Padagis US LLCNDC
00574232515
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA075529FDA Approved
2/22/2000
TE Code
AB
On Market Since
3/7/2017
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% GEL has been published 487 times since Apr 26, 2017, and over the history we have for it it has declined 9.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.7790 per GM |
|---|---|
| All-time high | $4.2866 (Dec 13, 2017) |
| All-time low | $2.4909 (Jul 17, 2024) |
| 52-week high | $3.7790 |
| 52-week low | $3.0067 |
| Median price | $3.7264 |
| Average price | $3.6751 |
| Largest weekly change | +22.3% (Jan 20, 2021) |
| Weeks tracked | 487 |
| Tracking since | Apr 26, 2017 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the tretinoin market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% GEL, manufactured by Padagis US LLC, is $3.7790 per GM (NDC 00574232515), effective Aug 19, 2026.
How has the price of TRETINOIN 0.025% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% GEL has declined 9.5%. It has been tracked across 487 weekly CMS publications since Apr 26, 2017.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% GEL?
Since Apr 26, 2017, the NADAC for TRETINOIN 0.025% GEL has ranged from a low of $2.4909 (Jul 17, 2024) to a high of $4.2866 (Dec 13, 2017), with a median of $3.7264 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% GEL?
No other NADAC-published product currently shares the active ingredient and strength of TRETINOIN 0.025% GEL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TRETINOIN 0.025% GEL?
TRETINOIN 0.025% GEL (NDC 00574232515) is labeled by Padagis US LLC, and CMS classifies it as a generic product.