Product Information

TRETINOIN 0.025% GEL is a generic product labeled by Padagis US LLC, priced at $2.7073 per GM under NDC 00574232545. Its NADAC has been published 450 times since Jan 10, 2018.

FDA first approved this application on Feb 22, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TRETINOIN 0.025% GEL

tretinoin
$2.7073per GM

Strength

.25 mg/g

Manufacturer

Padagis US LLC

NDC

00574232545

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

TRETINOIN

Approval Type

Generic (ANDA)

FDA Application

ANDA075529

FDA Approved

2/22/2000

TE Code

AB

On Market Since

3/7/2017

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for TRETINOIN 0.025% GEL has been published 450 times since Jan 10, 2018, and over the history we have for it it has declined 17.1%. The table below summarizes its recorded NADAC range and movement.

Current price$2.7073 per GM
All-time high$3.4247 (Oct 10, 2018)
All-time low$1.7252 (Jul 17, 2024)
52-week high$2.7073
52-week low$2.3908
Median price$2.5920
Average price$2.6814
Largest weekly change-34.8% (Nov 20, 2024)
Weeks tracked450
Tracking sinceJan 10, 2018

Price History

1W

+0.3%

1M

+0.3%

3M

+5.3%

6M

+9.9%

1Y

+11.7%

3Y

+0.2%

5Y

+9.8%

All

-17.1%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the tretinoin market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of TRETINOIN 0.025% GEL?

The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% GEL, manufactured by Padagis US LLC, is $2.7073 per GM (NDC 00574232545), effective Aug 19, 2026.

How has the price of TRETINOIN 0.025% GEL changed over time?

Over the history we have for it, the NADAC for TRETINOIN 0.025% GEL has declined 17.1%. It has been tracked across 450 weekly CMS publications since Jan 10, 2018.

What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% GEL?

Since Jan 10, 2018, the NADAC for TRETINOIN 0.025% GEL has ranged from a low of $1.7252 (Jul 17, 2024) to a high of $3.4247 (Oct 10, 2018), with a median of $2.5920 per GM.

Are there cheaper alternatives to TRETINOIN 0.025% GEL?

No other NADAC-published product currently shares the active ingredient and strength of TRETINOIN 0.025% GEL in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures TRETINOIN 0.025% GEL?

TRETINOIN 0.025% GEL (NDC 00574232545) is labeled by Padagis US LLC, and CMS classifies it as a generic product.