Product Information
TRETINOIN 0.025% GEL is a generic product labeled by Padagis US LLC, priced at $2.5002 per GM under NDC 00574232545. Its NADAC has been published 456 times since Jan 10, 2018.
FDA first approved this application on Feb 22, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Padagis US LLCNDC
00574232545
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA075529FDA Approved
2/22/2000
TE Code
AB
On Market Since
3/7/2017
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% GEL has been published 456 times since Jan 10, 2018, and over the history we have for it it has declined 23.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.5002 per GM |
|---|---|
| All-time high | $3.4247 (Oct 10, 2018) |
| All-time low | $1.7252 (Jul 17, 2024) |
| 52-week high | $2.7073 |
| 52-week low | $2.3908 |
| Median price | $2.5939 |
| Average price | $2.6808 |
| Largest weekly change | -34.8% (Nov 20, 2024) |
| Weeks tracked | 456 |
| Tracking since | Jan 10, 2018 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the tretinoin market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Padagis US LLC manufacturer profile
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Drug market
tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% GEL, manufactured by Padagis US LLC, is $2.5002 per GM (NDC 00574232545), effective Sep 30, 2026.
How has the price of TRETINOIN 0.025% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% GEL has declined 23.4%. It has been tracked across 456 weekly CMS publications since Jan 10, 2018.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% GEL?
Since Jan 10, 2018, the NADAC for TRETINOIN 0.025% GEL has ranged from a low of $1.7252 (Jul 17, 2024) to a high of $3.4247 (Oct 10, 2018), with a median of $2.5939 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% GEL?
No other NADAC-published product currently shares the active ingredient and strength of TRETINOIN 0.025% GEL in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures TRETINOIN 0.025% GEL?
TRETINOIN 0.025% GEL (NDC 00574232545) is labeled by Padagis US LLC, and CMS classifies it as a generic product.