Product Information
ESTRADIOL 0.0375 MG PATCH(1/WK) is a generic product labeled by Sandoz Inc., priced at $11.4381 per EA under NDC 00781712254. Its NADAC has been published 399 times since Nov 7, 2018.
Strength
.0375 mg/d
Manufacturer
Sandoz Inc.NDC
00781712254
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Authorized Generic (NDA)
FDA Application
NDA020375On Market Since
5/27/2003
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.0375 MG PATCH(1/WK) has been published 399 times since Nov 7, 2018, and over the history we have for it it has declined 21.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.4381 per EA |
|---|---|
| All-time high | $16.1747 (Mar 16, 2022) |
| All-time low | $9.4369 (Oct 18, 2023) |
| 52-week high | $12.2291 |
| 52-week low | $10.6248 |
| Median price | $13.2660 |
| Average price | $13.0234 |
| Largest weekly change | +40.2% (Nov 22, 2023) |
| Weeks tracked | 399 |
| Tracking since | Nov 7, 2018 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 32% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.0375 MG PATCH(1/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.0375 MG PATCH(1/WK), manufactured by Sandoz Inc., is $11.4381 per EA (NDC 00781712254), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.0375 MG PATCH(1/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.0375 MG PATCH(1/WK) has declined 21.4%. It has been tracked across 399 weekly CMS publications since Nov 7, 2018.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.0375 MG PATCH(1/WK)?
Since Nov 7, 2018, the NADAC for ESTRADIOL 0.0375 MG PATCH(1/WK) has ranged from a low of $9.4369 (Oct 18, 2023) to a high of $16.1747 (Mar 16, 2022), with a median of $13.2660 per EA.
Are there cheaper alternatives to ESTRADIOL 0.0375 MG PATCH(1/WK)?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, DOTTI 0.0375 MG PATCH, is $7.8091 per EA — about 32% below ESTRADIOL 0.0375 MG PATCH(1/WK).
Who manufactures ESTRADIOL 0.0375 MG PATCH(1/WK)?
ESTRADIOL 0.0375 MG PATCH(1/WK) (NDC 00781712254) is labeled by Sandoz Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification