Product Information
NALTREXONE 50 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $1.1392 per EA under NDC 00904703604. Its NADAC has been published 318 times since Jul 22, 2020.
FDA first approved this application on Feb 24, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904703604
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
NALTREXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090356FDA Approved
2/24/2012
TE Code
AB
On Market Since
2/29/2012
Pharmacological Classes
Price Statistics
The NADAC for NALTREXONE 50 MG TABLET has been published 318 times since Jul 22, 2020, and over the history we have for it it has risen 41.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1392 per EA |
|---|---|
| All-time high | $1.2957 (Nov 12, 2025) |
| All-time low | $0.6309 (Feb 22, 2023) |
| 52-week high | $1.2957 |
| 52-week low | $1.1392 |
| Median price | $0.7924 |
| Average price | $0.9067 |
| Largest weekly change | +23.3% (Aug 21, 2024) |
| Weeks tracked | 318 |
| Tracking since | Jul 22, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NALTREXONE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NALTREXONE 50 MG TABLET, manufactured by Major Pharmaceuticals, is $1.1392 per EA (NDC 00904703604), effective Aug 19, 2026.
How has the price of NALTREXONE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for NALTREXONE 50 MG TABLET has risen 41.7%. It has been tracked across 318 weekly CMS publications since Jul 22, 2020.
What are the highest and lowest recorded NADAC prices for NALTREXONE 50 MG TABLET?
Since Jul 22, 2020, the NADAC for NALTREXONE 50 MG TABLET has ranged from a low of $0.6309 (Feb 22, 2023) to a high of $1.2957 (Nov 12, 2025), with a median of $0.7924 per EA.
Are there cheaper alternatives to NALTREXONE 50 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as NALTREXONE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures NALTREXONE 50 MG TABLET?
NALTREXONE 50 MG TABLET (NDC 00904703604) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.