Strength
2; .5 mg/1; mg/1
Manufacturer
AvPAKNDC
50268014415
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Last Updated
6/17/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE DIHYDRATEApproval Type
Generic (ANDA)
FDA Application
ANDA203136On Market Since
12/8/2016
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has been published 450 times since Nov 15, 2017, and over the history we have for it it has declined 82.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4123 per EA |
|---|---|
| All-time high | $2.6511 (Jan 10, 2018) |
| All-time low | $0.3740 (Nov 20, 2024) |
| 52-week high | $0.5463 |
| 52-week low | $0.4123 |
| Median price | $0.7522 |
| Average price | $0.9822 |
| Largest weekly change | +58.5% (Aug 21, 2024) |
| Weeks tracked | 450 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, manufactured by AvPAK, is $0.4123 per EA (NDC 50268014415), effective Jun 24, 2026.
How has the price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has declined 82.4%. It has been tracked across 450 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?
Since Nov 15, 2017, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has ranged from a low of $0.3740 (Nov 20, 2024) to a high of $2.6511 (Jan 10, 2018), with a median of $0.7522 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?
9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, but none are currently priced below it.
Who manufactures BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?
BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET (NDC 50268014415) is labeled by AvPAK, and CMS classifies it as a generic product.
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