Product Information

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.4123 per EA under NDC 42858060103. Its NADAC has been published 256 times since Aug 4, 2021.

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET

Buprenorphine and Naloxone
$0.4123per EA
DEA Schedule CIII

Strength

2; .5 mg/1; mg/1

NDC

42858060103

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA205601

On Market Since

4/13/2020

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has been published 256 times since Aug 4, 2021, and over the history we have for it it has declined 61.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4123 per EA
All-time high$1.0654 (Aug 11, 2021)
All-time low$0.3740 (Nov 20, 2024)
52-week high$0.5463
52-week low$0.4123
Median price$0.5889
Average price$0.6001
Largest weekly change+58.5% (Aug 21, 2024)
Weeks tracked256
Tracking sinceAug 4, 2021

Price History

1W

0.0%

1M

-4.4%

3M

-14.3%

6M

-13.0%

1Y

-20.9%

3Y

-32.5%

5Y

N/A

All

-61.3%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $0.4123 per EA (NDC 42858060103), effective Jun 24, 2026.

How has the price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has declined 61.3%. It has been tracked across 256 weekly CMS publications since Aug 4, 2021.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

Since Aug 4, 2021, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has ranged from a low of $0.3740 (Nov 20, 2024) to a high of $1.0654 (Aug 11, 2021), with a median of $0.5889 per EA.

Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, but none are currently priced below it.

Who manufactures BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET (NDC 42858060103) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.