Product Information
ESTRADIOL 0.1% (0.25 MG) GEL PK is a generic product labeled by Trigen Laboratories, LLC, priced at $1.3810 per EA under NDC 13811009032. Its NADAC has been published 141 times since Oct 18, 2023.
Strength
.25 mg/.25g
Manufacturer
Trigen Laboratories, LLCNDC
13811009032
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038On Market Since
10/10/2022
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has been published 141 times since Oct 18, 2023, and over the history we have for it it has declined 59.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3810 per EA |
|---|---|
| All-time high | $3.7861 (Apr 10, 2024) |
| All-time low | $1.3233 (May 22, 2024) |
| 52-week high | $2.0942 |
| 52-week low | $1.3810 |
| Median price | $1.9492 |
| Average price | $2.1141 |
| Largest weekly change | +54.8% (Sep 18, 2024) |
| Weeks tracked | 141 |
| Tracking since | Oct 18, 2023 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (0.25 MG) GEL PK?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.25 MG) GEL PK, manufactured by Trigen Laboratories, LLC, is $1.3810 per EA (NDC 13811009032), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.1% (0.25 MG) GEL PK changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has declined 59.6%. It has been tracked across 141 weekly CMS publications since Oct 18, 2023.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.25 MG) GEL PK?
Since Oct 18, 2023, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has ranged from a low of $1.3233 (May 22, 2024) to a high of $3.7861 (Apr 10, 2024), with a median of $1.9492 per EA.
Are there cheaper alternatives to ESTRADIOL 0.1% (0.25 MG) GEL PK?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.1% (0.25 MG) GEL PK, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (0.25 MG) GEL PK?
ESTRADIOL 0.1% (0.25 MG) GEL PK (NDC 13811009032) is labeled by Trigen Laboratories, LLC, and CMS classifies it as a generic product.
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