Product Information
ESTRADIOL 0.1% (0.25 MG) GEL PK is a generic product labeled by NorthStar Rx LLC, priced at $1.3810 per EA under NDC 72603024130. Its NADAC has been published 117 times since Apr 3, 2024.
Strength
.25 mg/.25g
Manufacturer
NorthStar Rx LLCNDC
72603024130
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA217610On Market Since
12/18/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has been published 117 times since Apr 3, 2024, and over the history we have for it it has declined 63.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3810 per EA |
|---|---|
| All-time high | $3.7861 (Apr 10, 2024) |
| All-time low | $1.3233 (May 22, 2024) |
| 52-week high | $2.0942 |
| 52-week low | $1.3810 |
| Median price | $1.7427 |
| Average price | $1.8355 |
| Largest weekly change | +54.8% (Sep 18, 2024) |
| Weeks tracked | 117 |
| Tracking since | Apr 3, 2024 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (0.25 MG) GEL PK?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.25 MG) GEL PK, manufactured by NorthStar Rx LLC, is $1.3810 per EA (NDC 72603024130), effective Jun 24, 2026.
How has the price of ESTRADIOL 0.1% (0.25 MG) GEL PK changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has declined 63.5%. It has been tracked across 117 weekly CMS publications since Apr 3, 2024.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.25 MG) GEL PK?
Since Apr 3, 2024, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has ranged from a low of $1.3233 (May 22, 2024) to a high of $3.7861 (Apr 10, 2024), with a median of $1.7427 per EA.
Are there cheaper alternatives to ESTRADIOL 0.1% (0.25 MG) GEL PK?
3 NADAC-published products share the same active ingredient, strength, and dosage form as ESTRADIOL 0.1% (0.25 MG) GEL PK, but none are currently priced below it.
Who manufactures ESTRADIOL 0.1% (0.25 MG) GEL PK?
ESTRADIOL 0.1% (0.25 MG) GEL PK (NDC 72603024130) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.
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