Product Information
TRETINOIN GEL MICRO 0.08% PUMP is a generic product labeled by Encube Ethicals, Inc., priced at $11.6297 per GM under NDC 21922004340. Its NADAC has been published 123 times since Apr 17, 2024.
FDA first approved this application on Aug 22, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.8 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922004340
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA215609FDA Approved
8/22/2023
TE Code
AB
On Market Since
8/24/2023
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN GEL MICRO 0.08% PUMP has been published 123 times since Apr 17, 2024, and over the history we have for it it has risen 10.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.6297 per GM |
|---|---|
| All-time high | $12.6245 (Sep 10, 2025) |
| All-time low | $6.9402 (Feb 18, 2026) |
| 52-week high | $12.6245 |
| 52-week low | $6.9402 |
| Median price | $10.1786 |
| Average price | $9.9255 |
| Largest weekly change | +18.5% (Nov 20, 2024) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN GEL MICRO 0.08% PUMP?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN GEL MICRO 0.08% PUMP, manufactured by Encube Ethicals, Inc., is $11.6297 per GM (NDC 21922004340), effective Aug 19, 2026.
How has the price of TRETINOIN GEL MICRO 0.08% PUMP changed over time?
Over the history we have for it, the NADAC for TRETINOIN GEL MICRO 0.08% PUMP has risen 10.3%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for TRETINOIN GEL MICRO 0.08% PUMP?
Since Apr 17, 2024, the NADAC for TRETINOIN GEL MICRO 0.08% PUMP has ranged from a low of $6.9402 (Feb 18, 2026) to a high of $12.6245 (Sep 10, 2025), with a median of $10.1786 per GM.
Are there cheaper alternatives to TRETINOIN GEL MICRO 0.08% PUMP?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN GEL MICRO 0.08% PUMP in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN GEL MICRO 0.08% PUMP?
TRETINOIN GEL MICRO 0.08% PUMP (NDC 21922004340) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.