Product Information
ADAPALENE 0.3% GEL PUMP is a generic product labeled by Encube Ethicals, Inc., priced at $0.7822 per GM under NDC 21922005150. Its NADAC has been published 168 times since Jun 7, 2023.
FDA first approved this application on Jun 14, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
3 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922005150
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ADAPALENEApproval Type
Generic (ANDA)
FDA Application
ANDA200298FDA Approved
6/14/2012
TE Code
AB
On Market Since
8/7/2023
Pharmacological Classes
Price Statistics
The NADAC for ADAPALENE 0.3% GEL PUMP has been published 168 times since Jun 7, 2023, and over the history we have for it it has declined 60.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7822 per GM |
|---|---|
| All-time high | $2.0807 (Oct 11, 2023) |
| All-time low | $0.6628 (Jul 17, 2024) |
| 52-week high | $1.0433 |
| 52-week low | $0.7450 |
| Median price | $1.0080 |
| Average price | $1.1365 |
| Largest weekly change | -34.1% (Oct 18, 2023) |
| Weeks tracked | 168 |
| Tracking since | Jun 7, 2023 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 35% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ADAPALENE 0.3% GEL PUMP?
The current National Average Drug Acquisition Cost (NADAC) for ADAPALENE 0.3% GEL PUMP, manufactured by Encube Ethicals, Inc., is $0.7822 per GM (NDC 21922005150), effective Aug 19, 2026.
How has the price of ADAPALENE 0.3% GEL PUMP changed over time?
Over the history we have for it, the NADAC for ADAPALENE 0.3% GEL PUMP has declined 60.8%. It has been tracked across 168 weekly CMS publications since Jun 7, 2023.
What are the highest and lowest recorded NADAC prices for ADAPALENE 0.3% GEL PUMP?
Since Jun 7, 2023, the NADAC for ADAPALENE 0.3% GEL PUMP has ranged from a low of $0.6628 (Jul 17, 2024) to a high of $2.0807 (Oct 11, 2023), with a median of $1.0080 per GM.
Are there cheaper alternatives to ADAPALENE 0.3% GEL PUMP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ADAPALENE 0.3% GEL, is $0.5094 per GM — about 35% below ADAPALENE 0.3% GEL PUMP.
Who manufactures ADAPALENE 0.3% GEL PUMP?
ADAPALENE 0.3% GEL PUMP (NDC 21922005150) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.