Product Information
NALTREXONE 50 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $1.1375 per EA under NDC 23155088603. Its NADAC has been published 138 times since Feb 14, 2024.
FDA first approved this application on Jul 21, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Heritage Pharmaceuticals Inc.NDC
23155088603
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
NALTREXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA207905FDA Approved
7/21/2017
TE Code
AB
On Market Since
10/6/2023
Pharmacological Classes
Price Statistics
The NADAC for NALTREXONE 50 MG TABLET has been published 138 times since Feb 14, 2024, and over the history we have for it it has risen 24.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1375 per EA |
|---|---|
| All-time high | $1.2957 (Nov 12, 2025) |
| All-time low | $0.8382 (Apr 17, 2024) |
| 52-week high | $1.2957 |
| 52-week low | $1.1375 |
| Median price | $1.1392 |
| Average price | $1.1160 |
| Largest weekly change | +23.3% (Aug 21, 2024) |
| Weeks tracked | 138 |
| Tracking since | Feb 14, 2024 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Heritage Pharmaceuticals Inc. manufacturer profile
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Drug market
Naltrexone Hydrochloride market comparison
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Therapeutic class
Opioid Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of NALTREXONE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NALTREXONE 50 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $1.1375 per EA (NDC 23155088603), effective Sep 30, 2026.
How has the price of NALTREXONE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for NALTREXONE 50 MG TABLET has risen 24.3%. It has been tracked across 138 weekly CMS publications since Feb 14, 2024.
What are the highest and lowest recorded NADAC prices for NALTREXONE 50 MG TABLET?
Since Feb 14, 2024, the NADAC for NALTREXONE 50 MG TABLET has ranged from a low of $0.8382 (Apr 17, 2024) to a high of $1.2957 (Nov 12, 2025), with a median of $1.1392 per EA.
Are there cheaper alternatives to NALTREXONE 50 MG TABLET?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NALTREXONE 50 MG TABLET, is $0.8886 per EA — about 22% below NALTREXONE 50 MG TABLET.
Who manufactures NALTREXONE 50 MG TABLET?
NALTREXONE 50 MG TABLET (NDC 23155088603) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.