Product Information
BUPROPION HCL XL 300 MG TABLET is a generic product labeled by TWi Pharmaceuticals, Inc., priced at $0.1115 per EA under NDC 24979010207. Its NADAC has been published 405 times since Sep 26, 2018.
Strength
300 mg/1
Manufacturer
TWi Pharmaceuticals, Inc.NDC
24979010207
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210081On Market Since
8/30/2018
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 405 times since Sep 26, 2018, and over the history we have for it it has declined 72.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1115 per EA |
|---|---|
| All-time high | $0.4702 (Sep 11, 2019) |
| All-time low | $0.1033 (Feb 18, 2026) |
| 52-week high | $0.1504 |
| 52-week low | $0.1033 |
| Median price | $0.1795 |
| Average price | $0.2111 |
| Largest weekly change | -33.9% (Sep 18, 2019) |
| Weeks tracked | 405 |
| Tracking since | Sep 26, 2018 |
Generic Alternatives
The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by TWi Pharmaceuticals, Inc., is $0.1115 per EA (NDC 24979010207), effective Jun 24, 2026.
How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 72.9%. It has been tracked across 405 weekly CMS publications since Sep 26, 2018.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?
Since Sep 26, 2018, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.4702 (Sep 11, 2019), with a median of $0.1795 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?
9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.
Who manufactures BUPROPION HCL XL 300 MG TABLET?
BUPROPION HCL XL 300 MG TABLET (NDC 24979010207) is labeled by TWi Pharmaceuticals, Inc., and CMS classifies it as a generic product.
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