Product Information
BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.1115 per EA under NDC 42806041605. Its NADAC has been published 150 times since Aug 16, 2023.
Strength
300 mg/1
Manufacturer
Epic Pharma LLCNDC
42806041605
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA210015On Market Since
4/30/2023
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 150 times since Aug 16, 2023, and over the history we have for it it has declined 37.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1115 per EA |
|---|---|
| All-time high | $0.1988 (Feb 14, 2024) |
| All-time low | $0.1033 (Feb 18, 2026) |
| 52-week high | $0.1504 |
| 52-week low | $0.1033 |
| Median price | $0.1487 |
| Average price | $0.1478 |
| Largest weekly change | -27.4% (Feb 21, 2024) |
| Weeks tracked | 150 |
| Tracking since | Aug 16, 2023 |
Generic Alternatives
The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Epic Pharma LLC, is $0.1115 per EA (NDC 42806041605), effective Jun 24, 2026.
How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 37.4%. It has been tracked across 150 weekly CMS publications since Aug 16, 2023.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?
Since Aug 16, 2023, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.1988 (Feb 14, 2024), with a median of $0.1487 per EA.
Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?
9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.
Who manufactures BUPROPION HCL XL 300 MG TABLET?
BUPROPION HCL XL 300 MG TABLET (NDC 42806041605) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.
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