Product Information
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.6379 per EA under NDC 42858060203. Its NADAC has been published 264 times since Aug 4, 2021.
FDA first approved this application on Mar 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
8; 2 mg/1; mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858060203
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
8/19/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE DIHYDRATEApproval Type
Generic (ANDA)
FDA Application
ANDA205601FDA Approved
3/30/2020
TE Code
AB
On Market Since
4/13/2020
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has been published 264 times since Aug 4, 2021, and over the history we have for it it has declined 46.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6379 per EA |
|---|---|
| All-time high | $1.1932 (Aug 11, 2021) |
| All-time low | $0.6322 (Jul 22, 2026) |
| 52-week high | $0.7333 |
| 52-week low | $0.6322 |
| Median price | $0.9315 |
| Average price | $0.8837 |
| Largest weekly change | +29.6% (Aug 21, 2024) |
| Weeks tracked | 264 |
| Tracking since | Aug 4, 2021 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $0.6379 per EA (NDC 42858060203), effective Aug 19, 2026.
How has the price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has declined 46.5%. It has been tracked across 264 weekly CMS publications since Aug 4, 2021.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
Since Aug 4, 2021, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has ranged from a low of $0.6322 (Jul 22, 2026) to a high of $1.1932 (Aug 11, 2021), with a median of $0.9315 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET (NDC 42858060203) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.