Product Information
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET is a generic product labeled by AvPAK, priced at $0.6379 per EA under NDC 50268014515. Its NADAC has been published 458 times since Nov 15, 2017.
FDA first approved this application on Feb 22, 2013. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
8; 2 mg/1; mg/1
Manufacturer
AvPAKNDC
50268014515
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
8/19/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE DIHYDRATEApproval Type
Generic (ANDA)
FDA Application
ANDA203136FDA Approved
2/22/2013
TE Code
AB
On Market Since
12/8/2016
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has been published 458 times since Nov 15, 2017, and over the history we have for it it has declined 81.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6379 per EA |
|---|---|
| All-time high | $3.5241 (Nov 15, 2017) |
| All-time low | $0.6322 (Jul 22, 2026) |
| 52-week high | $0.7333 |
| 52-week low | $0.6322 |
| Median price | $1.0599 |
| Average price | $1.2815 |
| Largest weekly change | +29.6% (Aug 21, 2024) |
| Weeks tracked | 458 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET, manufactured by AvPAK, is $0.6379 per EA (NDC 50268014515), effective Aug 19, 2026.
How has the price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has declined 81.9%. It has been tracked across 458 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
Since Nov 15, 2017, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has ranged from a low of $0.6322 (Jul 22, 2026) to a high of $3.5241 (Nov 15, 2017), with a median of $1.0599 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET (NDC 50268014515) is labeled by AvPAK, and CMS classifies it as a generic product.