Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals Inc., priced at $0.1115 per EA under NDC 50228014530. Its NADAC has been published 303 times since Sep 9, 2020.

BUPROPION HCL XL 300 MG TABLET

bupropion hydrochloride
$0.1115per EA

Strength

300 mg/1

NDC

50228014530

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA207479

On Market Since

4/12/2017

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 303 times since Sep 9, 2020, and over the history we have for it it has declined 51.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.2793 (Oct 14, 2020)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1649
Average price$0.1695
Largest weekly change-27.4% (Feb 21, 2024)
Weeks tracked303
Tracking sinceSep 9, 2020

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

-35.5%

5Y

-45.5%

All

-51.5%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by ScieGen Pharmaceuticals Inc., is $0.1115 per EA (NDC 50228014530), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 51.5%. It has been tracked across 303 weekly CMS publications since Sep 9, 2020.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Sep 9, 2020, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.2793 (Oct 14, 2020), with a median of $0.1649 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 50228014530) is labeled by ScieGen Pharmaceuticals Inc., and CMS classifies it as a generic product.