Product Information
BUPROPION HCL SR 100 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.0687 per EA under NDC 50228017401. Its NADAC has been published 315 times since Aug 12, 2020.
FDA first approved this application on Mar 1, 2016. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
ScieGen Pharmaceuticals, Inc.NDC
50228017401
Classification
Generic
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205794FDA Approved
3/1/2016
TE Code
AB1
On Market Since
4/20/2018
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 315 times since Aug 12, 2020, and over the history we have for it it has declined 55.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0687 per EA |
|---|---|
| All-time high | $0.1760 (Sep 16, 2020) |
| All-time low | $0.0639 (Oct 22, 2025) |
| 52-week high | $0.0812 |
| 52-week low | $0.0639 |
| Median price | $0.1034 |
| Average price | $0.1045 |
| Largest weekly change | +30.2% (Jun 19, 2024) |
| Weeks tracked | 315 |
| Tracking since | Aug 12, 2020 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by ScieGen Pharmaceuticals, Inc., is $0.0687 per EA (NDC 50228017401), effective Aug 19, 2026.
How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 55.5%. It has been tracked across 315 weekly CMS publications since Aug 12, 2020.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?
Since Aug 12, 2020, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.1760 (Sep 16, 2020), with a median of $0.1034 per EA.
Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL SR 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL SR 100 MG TABLET?
BUPROPION HCL SR 100 MG TABLET (NDC 50228017401) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.