This NDC is on FDA's drug shortage list (posted Jul 26, 2023)

Reported reason: Discontinuation of the manufacture of the drug

Product Information

METHYLPHENIDATE ER 54 MG TAB is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.8329 per EA under NDC 57664060988. Its NADAC has been published 257 times since Jan 20, 2021.

FDA first approved this application on Aug 19, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METHYLPHENIDATE ER 54 MG TAB

Methylphenidate Hydrochloride
$0.8329per EA
DEA Schedule CII

Strength

54 mg/1

NDC

57664060988

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

12/17/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA205135

FDA Approved

8/19/2020

TE Code

AB

On Market Since

8/20/2020

Pharmacological Classes

Central Nervous System Stimulant
Central Nervous System Stimulation

Price Statistics

The NADAC for METHYLPHENIDATE ER 54 MG TAB has been published 257 times since Jan 20, 2021, and over the history we have for it it has declined 44.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.8329 per EA
All-time high$1.4916 (Feb 10, 2021)
All-time low$0.6051 (Feb 22, 2023)
52-week high$0.8562
52-week low$0.8294
Median price$0.8756
Average price$0.9431
Largest weekly change+71.1% (Nov 22, 2023)
Weeks tracked257
Tracking sinceJan 20, 2021

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-2.7%

3Y

-12.4%

5Y

-43.1%

All

-44.2%

Last surveyed Dec 17, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHYLPHENIDATE ER 54 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for METHYLPHENIDATE ER 54 MG TAB, manufactured by Sun Pharmaceutical Industries Inc., is $0.8329 per EA (NDC 57664060988), effective Dec 17, 2025.

How has the price of METHYLPHENIDATE ER 54 MG TAB changed over time?

Over the history we have for it, the NADAC for METHYLPHENIDATE ER 54 MG TAB has declined 44.2%. It has been tracked across 257 weekly CMS publications since Jan 20, 2021.

What are the highest and lowest recorded NADAC prices for METHYLPHENIDATE ER 54 MG TAB?

Since Jan 20, 2021, the NADAC for METHYLPHENIDATE ER 54 MG TAB has ranged from a low of $0.6051 (Feb 22, 2023) to a high of $1.4916 (Feb 10, 2021), with a median of $0.8756 per EA.

Are there cheaper alternatives to METHYLPHENIDATE ER 54 MG TAB?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHYLPHENIDATE ER 54 MG TAB, is $0.8092 per EA — about 3% below METHYLPHENIDATE ER 54 MG TAB.

Who manufactures METHYLPHENIDATE ER 54 MG TAB?

METHYLPHENIDATE ER 54 MG TAB (NDC 57664060988) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.

Is METHYLPHENIDATE ER 54 MG TAB in shortage?

Yes — NDC 57664060988 is currently listed in FDA's drug shortage database (posted Jul 26, 2023). Reported reason: Discontinuation of the manufacture of the drug.