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Product Information

ISOTRETINOIN 25 MG CAPSULE is a generic product labeled by Aurobindo Pharma Limited, priced at $10.8673 per EA under NDC 59651063303. Its NADAC has been published 82 times since Jan 29, 2025.

FDA first approved this application on Jan 29, 2024. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ISOTRETINOIN 25 MG CAPSULE

ISOTRETINOIN
$10.8673per EA

Strength

25 mg/1

NDC

59651063303

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ISOTRETINOIN

Approval Type

Generic (ANDA)

FDA Application

ANDA218194

FDA Approved

1/29/2024

TE Code

AB2

On Market Since

1/29/2024

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ISOTRETINOIN 25 MG CAPSULE has been published 82 times since Jan 29, 2025, and over the history we have for it it has declined 29.7%. The table below summarizes its recorded NADAC range and movement.

Current price$10.8673 per EA
All-time high$15.4591 (Mar 12, 2025)
All-time low$10.4672 (May 20, 2026)
52-week high$10.9483
52-week low$10.4672
Median price$10.9483
Average price$11.6973
Largest weekly change-13.2% (Apr 23, 2025)
Weeks tracked82
Tracking sinceJan 29, 2025

Price History

1W

+0.9%

1M

+0.9%

3M

+3.8%

6M

-0.7%

1Y

-0.7%

3Y

N/A

5Y

N/A

All

-29.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the ISOTRETINOIN market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of ISOTRETINOIN 25 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 25 MG CAPSULE, manufactured by Aurobindo Pharma Limited, is $10.8673 per EA (NDC 59651063303), effective Aug 19, 2026.

How has the price of ISOTRETINOIN 25 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for ISOTRETINOIN 25 MG CAPSULE has declined 29.7%. It has been tracked across 82 weekly CMS publications since Jan 29, 2025.

What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 25 MG CAPSULE?

Since Jan 29, 2025, the NADAC for ISOTRETINOIN 25 MG CAPSULE has ranged from a low of $10.4672 (May 20, 2026) to a high of $15.4591 (Mar 12, 2025), with a median of $10.9483 per EA.

Are there cheaper alternatives to ISOTRETINOIN 25 MG CAPSULE?

No other NADAC-published product currently shares the active ingredient and strength of ISOTRETINOIN 25 MG CAPSULE in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ISOTRETINOIN 25 MG CAPSULE?

ISOTRETINOIN 25 MG CAPSULE (NDC 59651063303) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.