Product Information
ISOTRETINOIN 25 MG CAPSULE is a generic product labeled by Aurobindo Pharma Limited, priced at $10.5512 per EA under NDC 59651063303. Its NADAC has been published 88 times since Jan 29, 2025.
FDA first approved this application on Jan 29, 2024. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
59651063303
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA218194FDA Approved
1/29/2024
TE Code
AB2
On Market Since
1/29/2024
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 25 MG CAPSULE has been published 88 times since Jan 29, 2025, and over the history we have for it it has declined 31.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.5512 per EA |
|---|---|
| All-time high | $15.4591 (Mar 12, 2025) |
| All-time low | $10.4672 (May 20, 2026) |
| 52-week high | $10.9483 |
| 52-week low | $10.4672 |
| Median price | $10.9483 |
| Average price | $11.6335 |
| Largest weekly change | -13.2% (Apr 23, 2025) |
| Weeks tracked | 88 |
| Tracking since | Jan 29, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the ISOTRETINOIN market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Aurobindo Pharma Limited manufacturer profile
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Drug market
ISOTRETINOIN market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ISOTRETINOIN 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 25 MG CAPSULE, manufactured by Aurobindo Pharma Limited, is $10.5512 per EA (NDC 59651063303), effective Sep 30, 2026.
How has the price of ISOTRETINOIN 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 25 MG CAPSULE has declined 31.7%. It has been tracked across 88 weekly CMS publications since Jan 29, 2025.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 25 MG CAPSULE?
Since Jan 29, 2025, the NADAC for ISOTRETINOIN 25 MG CAPSULE has ranged from a low of $10.4672 (May 20, 2026) to a high of $15.4591 (Mar 12, 2025), with a median of $10.9483 per EA.
Are there cheaper alternatives to ISOTRETINOIN 25 MG CAPSULE?
No other NADAC-published product currently shares the active ingredient and strength of ISOTRETINOIN 25 MG CAPSULE in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ISOTRETINOIN 25 MG CAPSULE?
ISOTRETINOIN 25 MG CAPSULE (NDC 59651063303) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.