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Product Information

NALOXONE HCL 4 MG NASAL SPRAY is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $16.9224 per EA under NDC 60219210407. Its NADAC has been published 92 times since Nov 20, 2024.

FDA first approved this application on Apr 23, 2024.

NALOXONE HCL 4 MG NASAL SPRAY

Naloxone
$16.9224per EA
OTC

Strength

4 mg/.1mL

NDC

60219210407

Classification

Generic

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

NALOXONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA217992

FDA Approved

4/23/2024

On Market Since

4/24/2024

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for NALOXONE HCL 4 MG NASAL SPRAY has been published 92 times since Nov 20, 2024, and over the history we have for it it has declined 35.0%. The table below summarizes its recorded NADAC range and movement.

Current price$16.9224 per EA
All-time high$29.0372 (Apr 16, 2025)
All-time low$15.2248 (May 20, 2026)
52-week high$23.1012
52-week low$15.2248
Median price$22.8128
Average price$21.6106
Largest weekly change-32.4% (Nov 19, 2025)
Weeks tracked92
Tracking sinceNov 20, 2024

Price History

1W

+6.6%

1M

+6.6%

3M

+11.2%

6M

+9.7%

1Y

-26.7%

3Y

N/A

5Y

N/A

All

-35.0%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Naloxone market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

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Frequently asked questions

What is the NADAC price of NALOXONE HCL 4 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for NALOXONE HCL 4 MG NASAL SPRAY, manufactured by Amneal Pharmaceuticals NY LLC, is $16.9224 per EA (NDC 60219210407), effective Aug 19, 2026.

How has the price of NALOXONE HCL 4 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has declined 35.0%. It has been tracked across 92 weekly CMS publications since Nov 20, 2024.

What are the highest and lowest recorded NADAC prices for NALOXONE HCL 4 MG NASAL SPRAY?

Since Nov 20, 2024, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has ranged from a low of $15.2248 (May 20, 2026) to a high of $29.0372 (Apr 16, 2025), with a median of $22.8128 per EA.

Are there cheaper alternatives to NALOXONE HCL 4 MG NASAL SPRAY?

No other NADAC-published product currently shares the active ingredient and strength of NALOXONE HCL 4 MG NASAL SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures NALOXONE HCL 4 MG NASAL SPRAY?

NALOXONE HCL 4 MG NASAL SPRAY (NDC 60219210407) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.