Product Information

TRAMADOL HCL 50 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0245 per EA under NDC 64980061410. Its NADAC has been published 32 times since Jan 14, 2026.

FDA first approved this application on Jun 25, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TRAMADOL HCL 50 MG TABLET

Tramadol Hydrochloride
$0.0245per EA
DEA Schedule CIV

Strength

50 mg/1

NDC

64980061410

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

TRAMADOL HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075968

FDA Approved

6/25/2002

TE Code

AB

On Market Since

8/5/2024

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for TRAMADOL HCL 50 MG TABLET has been published 32 times since Jan 14, 2026, and over the history we have for it it has risen 3.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0245 per EA
All-time high$0.0245 (Aug 19, 2026)
All-time low$0.0235 (Jul 22, 2026)
52-week high$0.0245
52-week low$0.0235
Median price$0.0239
Average price$0.0238
Largest weekly change+4.3% (Aug 19, 2026)
Weeks tracked32
Tracking sinceJan 14, 2026

Price History

1W

+4.3%

1M

+4.3%

3M

+3.7%

6M

+2.8%

1Y

N/A

3Y

N/A

5Y

N/A

All

+3.6%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TRAMADOL HCL 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 50 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0245 per EA (NDC 64980061410), effective Aug 19, 2026.

How has the price of TRAMADOL HCL 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for TRAMADOL HCL 50 MG TABLET has risen 3.6%. It has been tracked across 32 weekly CMS publications since Jan 14, 2026.

What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 50 MG TABLET?

Since Jan 14, 2026, the NADAC for TRAMADOL HCL 50 MG TABLET has ranged from a low of $0.0235 (Jul 22, 2026) to a high of $0.0245 (Aug 19, 2026), with a median of $0.0239 per EA.

Are there cheaper alternatives to TRAMADOL HCL 50 MG TABLET?

Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRAMADOL HCL 50 MG TABLET, is $0.0239 per EA — about 3% below TRAMADOL HCL 50 MG TABLET.

Who manufactures TRAMADOL HCL 50 MG TABLET?

TRAMADOL HCL 50 MG TABLET (NDC 64980061410) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.