Product Information
TRAMADOL HCL 50 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0248 per EA under NDC 64980061410. Its NADAC has been published 38 times since Jan 14, 2026.
FDA first approved this application on Jun 25, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
64980061410
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075968FDA Approved
6/25/2002
TE Code
AB
On Market Since
8/5/2024
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 50 MG TABLET has been published 38 times since Jan 14, 2026, and over the history we have for it it has risen 4.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0248 per EA |
|---|---|
| All-time high | $0.0248 (Sep 30, 2026) |
| All-time low | $0.0235 (Jul 22, 2026) |
| 52-week high | $0.0248 |
| 52-week low | $0.0235 |
| Median price | $0.0239 |
| Average price | $0.0240 |
| Largest weekly change | +4.3% (Aug 19, 2026) |
| Weeks tracked | 38 |
| Tracking since | Jan 14, 2026 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
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Drug market
Tramadol Hydrochloride market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 50 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0248 per EA (NDC 64980061410), effective Sep 30, 2026.
How has the price of TRAMADOL HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 50 MG TABLET has risen 4.7%. It has been tracked across 38 weekly CMS publications since Jan 14, 2026.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 50 MG TABLET?
Since Jan 14, 2026, the NADAC for TRAMADOL HCL 50 MG TABLET has ranged from a low of $0.0235 (Jul 22, 2026) to a high of $0.0248 (Sep 30, 2026), with a median of $0.0239 per EA.
Are there cheaper alternatives to TRAMADOL HCL 50 MG TABLET?
Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRAMADOL HCL 50 MG TABLET, is $0.0239 per EA — about 4% below TRAMADOL HCL 50 MG TABLET.
Who manufactures TRAMADOL HCL 50 MG TABLET?
TRAMADOL HCL 50 MG TABLET (NDC 64980061410) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.