Product Information
VIVELLE-DOT 0.075 MG PATCH is a brand product labeled by Sandoz Inc., priced at $18.4300 per EA under NDC 66758014883. Its NADAC has been published 98 times since Nov 20, 2024.
FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.075 mg/d
Manufacturer
Sandoz Inc.NDC
66758014883
Classification
Brand
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020538FDA Approved
1/8/1999
TE Code
AB1
On Market Since
1/8/1999
Pharmacological Classes
Price Statistics
The NADAC for VIVELLE-DOT 0.075 MG PATCH has been published 98 times since Nov 20, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.4300 per EA |
|---|---|
| All-time high | $18.4683 (Dec 11, 2024) |
| All-time low | $18.4033 (Nov 19, 2025) |
| 52-week high | $18.4383 |
| 52-week low | $18.4033 |
| Median price | $18.4307 |
| Average price | $18.4306 |
| Largest weekly change | +0.2% (May 21, 2025) |
| Weeks tracked | 98 |
| Tracking since | Nov 20, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 56% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Sandoz Inc. manufacturer profile
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Therapeutic class
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of VIVELLE-DOT 0.075 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for VIVELLE-DOT 0.075 MG PATCH, manufactured by Sandoz Inc., is $18.4300 per EA (NDC 66758014883), effective Sep 30, 2026.
How has the price of VIVELLE-DOT 0.075 MG PATCH changed over time?
Over the history we have for it, the NADAC for VIVELLE-DOT 0.075 MG PATCH has held within roughly two percent of its current level. It has been tracked across 98 weekly CMS publications since Nov 20, 2024.
What are the highest and lowest recorded NADAC prices for VIVELLE-DOT 0.075 MG PATCH?
Since Nov 20, 2024, the NADAC for VIVELLE-DOT 0.075 MG PATCH has ranged from a low of $18.4033 (Nov 19, 2025) to a high of $18.4683 (Dec 11, 2024), with a median of $18.4307 per EA.
Are there cheaper alternatives to VIVELLE-DOT 0.075 MG PATCH?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.075 MG PATCH(2/WK), is $8.1128 per EA — about 56% below VIVELLE-DOT 0.075 MG PATCH.
Who manufactures VIVELLE-DOT 0.075 MG PATCH?
VIVELLE-DOT 0.075 MG PATCH (NDC 66758014883) is labeled by Sandoz Inc., and CMS classifies it as a brand product.