Product Information
ESTRADIOL 0.075 MG PATCH(2/WK) is a generic product labeled by Sandoz Inc., priced at $8.0918 per EA under NDC 00781715683. Its NADAC has been published 533 times since Jun 8, 2016.
FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.075 mg/d
Manufacturer
Sandoz Inc.NDC
00781715683
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Authorized Generic (NDA)
FDA Application
NDA020538FDA Approved
1/8/1999
TE Code
AB1
On Market Since
12/22/2014
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has been published 533 times since Jun 8, 2016, and over the history we have for it it has declined 6.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.0918 per EA |
|---|---|
| All-time high | $9.3768 (Mar 10, 2021) |
| All-time low | $5.2541 (May 22, 2024) |
| 52-week high | $8.0918 |
| 52-week low | $6.8560 |
| Median price | $7.6160 |
| Average price | $7.6086 |
| Largest weekly change | +31.0% (Jun 19, 2024) |
| Weeks tracked | 533 |
| Tracking since | Jun 8, 2016 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.075 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.075 MG PATCH(2/WK), manufactured by Sandoz Inc., is $8.0918 per EA (NDC 00781715683), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.075 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has declined 6.5%. It has been tracked across 533 weekly CMS publications since Jun 8, 2016.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.075 MG PATCH(2/WK)?
Since Jun 8, 2016, the NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has ranged from a low of $5.2541 (May 22, 2024) to a high of $9.3768 (Mar 10, 2021), with a median of $7.6160 per EA.
Are there cheaper alternatives to ESTRADIOL 0.075 MG PATCH(2/WK)?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.075 MG PATCH(2/WK) in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.075 MG PATCH(2/WK)?
ESTRADIOL 0.075 MG PATCH(2/WK) (NDC 00781715683) is labeled by Sandoz Inc., and CMS classifies it as a generic product.