Product Information
ESTRADIOL 0.075 MG PATCH(2/WK) is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $8.0918 per EA under NDC 00378464126. Its NADAC has been published 597 times since Mar 18, 2015.
FDA first approved this application on Dec 19, 2014. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.075 mg/d
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378464126
Classification
Generic
Dosage Form
PATCH
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA201675FDA Approved
12/19/2014
TE Code
AB1
On Market Since
12/19/2014
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has been published 597 times since Mar 18, 2015, and over the history we have for it it has declined 11.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.0918 per EA |
|---|---|
| All-time high | $9.3768 (Mar 10, 2021) |
| All-time low | $5.2541 (May 22, 2024) |
| 52-week high | $8.0918 |
| 52-week low | $6.8560 |
| Median price | $7.8253 |
| Average price | $7.7492 |
| Largest weekly change | +31.0% (Jun 19, 2024) |
| Weeks tracked | 597 |
| Tracking since | Mar 18, 2015 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.075 MG PATCH(2/WK)?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.075 MG PATCH(2/WK), manufactured by Mylan Pharmaceuticals Inc., is $8.0918 per EA (NDC 00378464126), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.075 MG PATCH(2/WK) changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has declined 11.2%. It has been tracked across 597 weekly CMS publications since Mar 18, 2015.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.075 MG PATCH(2/WK)?
Since Mar 18, 2015, the NADAC for ESTRADIOL 0.075 MG PATCH(2/WK) has ranged from a low of $5.2541 (May 22, 2024) to a high of $9.3768 (Mar 10, 2021), with a median of $7.8253 per EA.
Are there cheaper alternatives to ESTRADIOL 0.075 MG PATCH(2/WK)?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ESTRADIOL 0.075 MG PATCH(2/WK) in a comparable dosage form, but none are currently priced below it.
Who manufactures ESTRADIOL 0.075 MG PATCH(2/WK)?
ESTRADIOL 0.075 MG PATCH(2/WK) (NDC 00378464126) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.