Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1115 per EA under NDC 68180032006. Its NADAC has been published 463 times since Aug 16, 2017.

BUPROPION HCL XL 300 MG TABLET

Bupropion Hydrochloride
$0.1115per EA

Strength

300 mg/1

NDC

68180032006

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA090693

On Market Since

6/14/2017

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 463 times since Aug 16, 2017, and over the history we have for it it has declined 76.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.4803 (Aug 16, 2017)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1946
Average price$0.2393
Largest weekly change-33.9% (Sep 18, 2019)
Weeks tracked463
Tracking sinceAug 16, 2017

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

-35.5%

5Y

-45.5%

All

-76.8%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.1115 per EA (NDC 68180032006), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 76.8%. It has been tracked across 463 weekly CMS publications since Aug 16, 2017.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Aug 16, 2017, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.4803 (Aug 16, 2017), with a median of $0.1946 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 68180032006) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.