Product Information

ISOTRETINOIN 20 MG CAPSULE is a generic product labeled by Mayne Pharma, priced at $5.9704 per EA under NDC 68308057130. Its NADAC has been published 191 times since Nov 3, 2021.

ISOTRETINOIN 20 MG CAPSULE

Isotretinoin
$5.9704per EA

Strength

20 mg/1

Manufacturer

Mayne Pharma

NDC

68308057130

Classification

Generic

Dosage Form

CAPSULE, LIQUID FILLED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

ISOTRETINOIN

Approval Type

Generic (ANDA)

FDA Application

ANDA212333

On Market Since

9/21/2021

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ISOTRETINOIN 20 MG CAPSULE has been published 191 times since Nov 3, 2021, and over the history we have for it it has declined 75.9%. The table below summarizes its recorded NADAC range and movement.

Current price$5.9704 per EA
All-time high$24.8070 (Jun 15, 2022)
All-time low$5.9704 (Jun 17, 2026)
52-week high$9.6413
52-week low$5.9704
Median price$15.5418
Average price$15.0387
Largest weekly change-23.0% (Jun 21, 2023)
Weeks tracked191
Tracking sinceNov 3, 2021

Price History

1W

0.0%

1M

-5.5%

3M

-23.8%

6M

-34.4%

1Y

-38.1%

3Y

-68.7%

5Y

N/A

All

-75.9%

Generic Alternatives

The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 68% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ISOTRETINOIN 20 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 20 MG CAPSULE, manufactured by Mayne Pharma, is $5.9704 per EA (NDC 68308057130), effective Jun 24, 2026.

How has the price of ISOTRETINOIN 20 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for ISOTRETINOIN 20 MG CAPSULE has declined 75.9%. It has been tracked across 191 weekly CMS publications since Nov 3, 2021.

What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 20 MG CAPSULE?

Since Nov 3, 2021, the NADAC for ISOTRETINOIN 20 MG CAPSULE has ranged from a low of $5.9704 (Jun 17, 2026) to a high of $24.8070 (Jun 15, 2022), with a median of $15.5418 per EA.

Are there cheaper alternatives to ISOTRETINOIN 20 MG CAPSULE?

Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ISOTRETINOIN 20 MG CAPSULE, is $1.8955 per EA — about 68% below ISOTRETINOIN 20 MG CAPSULE.

Who manufactures ISOTRETINOIN 20 MG CAPSULE?

ISOTRETINOIN 20 MG CAPSULE (NDC 68308057130) is labeled by Mayne Pharma, and CMS classifies it as a generic product.